Ganglion Impar Block and Neurolysis for Perineal Pain in Anal Adenocarcinoma: A Case Report

Q3 Pharmacology, Toxicology and Pharmaceutics Pharmacognosy Journal Pub Date : 2024-07-01 DOI:10.5530/pj.2024.16.120
Asmaranto Asmaranto, Dedi Susila
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Abstract

sides and the posterior vagina/labia minora. The patient was diagnosed with adenomakarsinoma anus and underwent 25 sessions of chemotherapy. Despite taking analgesics such as oral morphine, tramadol, codeine, and paracetamol, the patient's pain persisted with a score of 7-8 on the NRS (Numeric Rating Scale). The patient was scheduled for a ganglion impar block using a neurolytic agent ABSTRACT Background : Anal adenocarcinoma is a rare malignancy with symptoms including tenesmus, rectal bleeding, and pain during defecation. The pain can significantly reduce a patient's quality of life and there is currently no effective treatment for it. Ganglion impar block and neurolytic are one methods for managing pain in such cases. Case : A 60-year-old woman with anal adenocarcinoma and chronic pain in the anal region for two years despite oral medication underwent ganglion impar block and neurolytic treatment using a mixture of 96% alcohol and levobupivacaine 0.25%. Conclusion : Ganglion impar block with neurolysis using 96% alcohol can be an option for managing perineal pain, especially when previous medication therapy is ineffective. This combination is safe for patients and can reduce pain levels.
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肛门腺癌患者会阴疼痛的神经节假体阻滞和神经切除术:病例报告
两侧和后阴道/小阴唇。患者被诊断为肛门腺瘤,接受了 25 次化疗。尽管患者口服了吗啡、曲马多、可待因和扑热息痛等镇痛药,但疼痛仍持续存在,NRS(数字评分量表)评分为 7-8。ABSTRACT 背景:肛门腺癌是一种罕见的恶性肿瘤,其症状包括肛门疼痛、直肠出血和排便时疼痛。疼痛会大大降低患者的生活质量,目前尚无有效的治疗方法。神经节阻滞和神经溶解术是治疗此类疼痛的一种方法。病例:一名 60 岁的妇女患有肛门腺癌,尽管口服药物治疗,但肛门区域仍有两年的慢性疼痛,她接受了神经节阻滞和神经溶解治疗,使用的是 96% 酒精和 0.25% 左旋布比卡因的混合物。结论:使用 96% 酒精进行神经节阻滞和神经溶解治疗是治疗会阴疼痛的一种选择,尤其是在之前的药物治疗无效的情况下。这种组合对患者来说是安全的,并能减轻疼痛程度。
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来源期刊
Pharmacognosy Journal
Pharmacognosy Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
2.20
自引率
0.00%
发文量
151
期刊介绍: In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs. Pharmacognosy Journal (Phcog J.) is one of the six journals published by Phcog.Net, Each issue covers different topics in natural product drug discovery, and also publishes manuscripts that describe pharmacognostic investigations, evaluation reports, methods, techniques and applications of all forms of medicinal plant research
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