Quality of life in oncological patients with venous thromboembolic disease

Abstract

Venous thromboembolic disease (VTE) is a significant medical problem in cancer patients, as it is associated with substantial morbidity and increased mortality. Cancer survivors with VTE experience important changes in their health-related quality of life (HRQOL). Over the past few years, HRQOL and its measurement have been incorporated in clinical studies of anticoagulation therapy, as well as in qualitative and quantitative studies for the examination of the impact of VTE in cancer patients. While there are several tools available to assess HRQOL, few are specific to cancer patients and VTE. More importantly, those same tools are yet to be incorporated in routine clinical practice. The purpose of this review is to describe the available tools for the assessment of HRQOL in cancer patients with a focus on VTE, as well as the characteristics of those tools, their strengths, limitations, and potential applicability in clinical practice.