Seroprevalence of Dengue and Hepatitis B infections among young adults attending a secondary health care facility at Olabisi Onabanjo University, Ogun State, Nigeria

H. Adekola, Georgia Agu, F. A. Odeyemi, Haneefat Egberongbe, Ismail Onajobi, Wahab Kareem, Oyesanya Adejonwo
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Abstract

Hepatitis B and Dengue virus infections carry significant public health implications due to their potential to cause illness and death. This study focused on examining the prevalence of these infections among young adults seeking care at a secondary health facility at Olabisi Onabanjo University. Ninety samples obtained from study participants underwent screening using Enzyme-linked Immunosorbent Assay (ELISA) for both HBsAg and Dengue IgM. The participants, predominantly female, were aged between 15 and 30 years. The analysis revealed a 13.3% prevalence of Dengue IgM, a 4.5% prevalence of HBsAg, and a 4.4% prevalence for both infections. Regarding age distribution, the highest prevalence occurred among participants aged 15-20 years for both single infections and the co-occurrence of Hepatitis B and Dengue viral infections. Examining gender distribution, female participants exhibited higher seropositivity across all infection categories. Although not statistically significant, these findings lay the groundwork for a comprehensive surveillance study on the Hepatitis B and Dengue viral infections in young adults. This study provides valuable insights into the prevalence patterns of Hepatitis B and Dengue virus, offering a basis for further research and public health interventions in this population.
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尼日利亚奥贡州奥拉比西-奥纳班霍大学二级医疗机构就诊的年轻人中登革热和乙肝感染的血清流行率
乙型肝炎和登革热病毒感染可能导致疾病和死亡,对公共卫生具有重大影响。这项研究的重点是检查在奥拉比西-奥纳班霍大学的一家二级医疗机构就医的年轻人中这两种病毒的感染率。研究人员使用酶联免疫吸附试验(ELISA)对 90 份样本进行了乙肝表面抗原(HBsAg)和登革热 IgM 的筛查。参与者主要为女性,年龄在 15 至 30 岁之间。分析结果显示,登革热 IgM 感染率为 13.3%,HBsAg 感染率为 4.5%,两种感染率均为 4.4%。在年龄分布方面,15-20 岁参与者的感染率最高,无论是单一感染还是同时感染乙肝和登革热病毒。在性别分布方面,女性参与者在所有感染类别中都表现出较高的血清阳性率。尽管在统计学上没有意义,但这些发现为在青壮年中开展乙型肝炎和登革热病毒感染的全面监测研究奠定了基础。这项研究为了解乙型肝炎和登革热病毒的流行模式提供了有价值的见解,为在这一人群中开展进一步研究和采取公共卫生干预措施奠定了基础。
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