Anabolic treatment for osteoporosis and fragility fracture risk: one year in review 2024.

IF 3.4 4区 医学 Q2 RHEUMATOLOGY Clinical and experimental rheumatology Pub Date : 2024-07-01 Epub Date: 2024-07-18 DOI:10.55563/clinexprheumatol/7f52vl
Giammarco De Mattia, Michele Maffi, Maurizio Mazzantini
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Abstract

Osteoporosis is a skeletal disease characterised by reduced bone mass and deterioration of bone microarchitecture, underlying a higher risk of fragility fractures. Several options are available for its treatment, including both anti-resorptive and anabolic agents. The present review discusses and summarises the most recent literature on anabolic treatment, with a focus on abaloparatide, and on the assessment of fragility fracture risk, with a focus on trabecular bone score. Finally, we provide a discussion on the effects of different antiosteoporotic medications in terms of fragility fracture risk reduction.

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骨质疏松症和脆性骨折风险的同化治疗:2024 年回顾一年。
骨质疏松症是一种骨骼疾病,其特点是骨量减少和骨微结构退化,脆性骨折的风险较高。目前有多种治疗骨质疏松症的方法,包括抗骨质吸收剂和同化制剂。本综述讨论并总结了有关同化治疗(重点是阿巴帕肽)和脆性骨折风险评估(重点是骨小梁评分)的最新文献。最后,我们还讨论了不同抗骨质疏松药物在降低脆性骨折风险方面的效果。
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来源期刊
CiteScore
6.10
自引率
18.90%
发文量
377
审稿时长
3-6 weeks
期刊介绍: Clinical and Experimental Rheumatology is a bi-monthly international peer-reviewed journal which has been covering all clinical, experimental and translational aspects of musculoskeletal, arthritic and connective tissue diseases since 1983.
期刊最新文献
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