Association of Abdominal Aortic Calcification and Clinical Outcomes in LDH Patients Treated with Endoscopic Lumbar Discectomy.

IF 4.1 2区 医学 Q1 CLINICAL NEUROLOGY Pain and Therapy Pub Date : 2024-10-01 Epub Date: 2024-07-19 DOI:10.1007/s40122-024-00633-2
Ying Zhang, Zhaoji Zhu, Xiaohong Jin, Peng Huang
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Abstract

Introduction: To determine any significant associations between abdominal aortic calcification (AAC) and clinical manifestations of pain symptoms following endoscopic lumbar discectomy.

Methods: Patients sequentially presenting with a history of unilateral radiculopathy with or without back pain, and with magnetic resonance imaging (MRI)-confirmed diagnosis of posterolateral disc herniation between August 2021 and December 2023 were eligible for inclusion in the study. All patients underwent endoscopic discectomy at our center during the study period. AAC stages were classified based on the Kauppila classification system using lateral lumbar radiographs.

Results: Between August 2021 and December 2023 a total of 120 patients were included in the study for analysis, of whom 82 (68.3%) exhibited mild AAC and 38 (31.7%) had moderate-severe AAC. Analyses using the multivariate linear regression model revealed a significant correlation between AAC comorbidity and postoperative clinical outcomes. At 1 year post-surgery, the mean change in leg pain following endoscopic lumbar discectomy was significantly less for patients with moderate-severe AAC (5.0 points) than for patients with mild ACC (p < 0.001). Even after adjusting for relevant confounders, this difference remained significant. Similar results were also observed in the postoperative improvement of back pain, the Oswestry Disability Index score, and the physical functioning, role physical, and bodily pain components of the 36-item Short Form Health Survey questionnaire. There was no significant difference in the rate of repeat surgery or post-surgical new-onset back pain between patients with different levels of severity of AAC at 1 year post-surgery.

Conclusions: There is a significant association between the severity of AAC and clinical outcomes among patients with lumbar disk herniation who underwent endoscopic lumbar discectomy. AAC may serve as a prognostic factor in predicting surgical outcomes and guiding management strategies for patients with lumbar disk herniation following endoscopic lumbar discectomy.

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接受内窥镜腰椎间盘切除术的 LDH 患者腹主动脉钙化与临床疗效的关系
引言目的:确定腹主动脉钙化(AAC)与内窥镜腰椎间盘切除术后疼痛症状的临床表现之间是否存在明显关联:研究对象为2021年8月至2023年12月期间连续出现单侧根性腰痛病史,伴有或不伴有腰痛,并经磁共振成像(MRI)确诊为后外侧椎间盘突出症的患者。研究期间,所有患者均在本中心接受了内窥镜椎间盘切除术。AAC分期根据Kauppila分类系统,使用腰椎侧位X光片进行分类:2021年8月至2023年12月期间,共有120名患者被纳入研究进行分析,其中82人(68.3%)为轻度AAC,38人(31.7%)为中重度AAC。使用多变量线性回归模型进行的分析表明,AAC 合并症与术后临床结果之间存在显著相关性。术后 1 年,中重度 AAC 患者在内镜下腰椎间盘切除术后腿痛的平均变化(5.0 分)明显低于轻度 ACC 患者(P 结论:中重度 AAC 患者在内镜下腰椎间盘切除术后腿痛的平均变化(5.0 分)明显低于轻度 ACC 患者:在接受内窥镜腰椎间盘切除术的腰椎间盘突出症患者中,AAC 的严重程度与临床预后之间存在明显关联。AAC可作为内窥镜腰椎间盘切除术后预测手术效果和指导腰椎间盘突出症患者管理策略的预后因素。
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来源期刊
Pain and Therapy
Pain and Therapy CLINICAL NEUROLOGY-
CiteScore
6.60
自引率
5.00%
发文量
110
审稿时长
6 weeks
期刊介绍: Pain and Therapy is an international, open access, peer-reviewed, rapid publication journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of pain therapies and pain-related devices. Studies relating to diagnosis, pharmacoeconomics, public health, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to, acute pain, cancer pain, chronic pain, headache and migraine, neuropathic pain, opioids, palliative care and pain ethics, peri- and post-operative pain as well as rheumatic pain and fibromyalgia. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports, trial protocols, short communications such as commentaries and editorials, and letters. The journal is read by a global audience and receives submissions from around the world. Pain and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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