Less common forms of diabetes in young population.

Anna Tekielak, Ewa Otto-Buczkowska, Ewa Rusak
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Abstract

Types diabetes other than type 1 are generally considered rare in children and adolescents. The incidence of type 2 diabetes has increased dramatically over the past decade in some ethnic groups. The increased incidence of this type of diabetes mellitus has corresponded tem-porally to unprecedented increases in body weight and obesity prevalence in adolescents in various ethnic populations. Early treatment of insulin resistance is important to prevent the development of diabetes. In therapy, lifestyle modification is essential for weight loss, and if this is not enough, pharmacotherapy is required. Maturity-onset diabetes of the young (MODY), another type of insulin-dependent diabetes, is characterised by early onset and autosomal dominant inheritance. MODY is mainly caused by β-cell defects, resulting in insufficient insulin secretion for a given blood glucose level. Unlike non-insulin-dependent diabetes in youth (NIDDM-Y), there is no significant increase in insulin resistance. The purpose of this article is to characterise and present types of diabetes other than type 1 found in the young population.

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年轻人中较少见的糖尿病。
一般认为,除 1 型糖尿病外,其他类型的糖尿病在儿童和青少年中很少见。在过去十年中,2 型糖尿病的发病率在一些种族群体中急剧上升。2 型糖尿病发病率的增加与不同种族青少年体重和肥胖率的空前增长是同步的。早期治疗胰岛素抵抗对预防糖尿病的发展非常重要。在治疗过程中,改变生活方式对减轻体重至关重要,如果还不够,则需要药物治疗。成熟期发病的青年糖尿病(MODY)是另一种胰岛素依赖型糖尿病,其特点是发病早和常染色体显性遗传。MODY主要由β细胞缺陷引起,导致在一定血糖水平下胰岛素分泌不足。与青少年非胰岛素依赖型糖尿病(NIDDM-Y)不同的是,胰岛素抵抗并没有明显增加。本文旨在描述和介绍在年轻人群中发现的 1 型糖尿病以外的糖尿病类型。
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来源期刊
Pediatric Endocrinology, Diabetes and Metabolism
Pediatric Endocrinology, Diabetes and Metabolism Medicine-Pediatrics, Perinatology and Child Health
CiteScore
2.00
自引率
0.00%
发文量
36
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