Neurological insights into brain-targeted cancer therapy and bioinspired microrobots

IF 6.5 2区 医学 Q1 PHARMACOLOGY & PHARMACY Drug Discovery Today Pub Date : 2024-07-17 DOI:10.1016/j.drudis.2024.104105
Shampa Ghosh , Rakesh Bhaskar , Richa Mishra , M. Arockia Babu , Mosleh Mohammad Abomughaid , Niraj Kumar Jha , Jitendra Kumar Sinha
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Abstract

Cancer, a multifaceted and pernicious disease, continuously challenges medicine, requiring innovative treatments. Brain cancers pose unique and daunting challenges due to the intricacies of the central nervous system and the blood–brain barrier. In this era of precision medicine, the convergence of neurology, oncology, and cutting-edge technology has given birth to a promising avenue – targeted cancer therapy. Furthermore, bioinspired microrobots have emerged as an ingenious approach to drug delivery, enabling precision and control in cancer treatment. This Keynote review explores the intricate web of neurological insights into brain-targeted cancer therapy and the paradigm-shifting world of bioinspired microrobots. It serves as a critical and comprehensive overview of these evolving fields, aiming to underscore their integration and potential for revolutionary cancer treatments.

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脑靶向癌症疗法和生物启发微型机器人的神经学见解。
癌症是一种多方面的恶性疾病,不断对医学提出挑战,需要创新的治疗方法。由于中枢神经系统和血脑屏障的复杂性,脑癌带来了独特而艰巨的挑战。在这个精准医疗的时代,神经学、肿瘤学和尖端技术的融合催生了一条前景广阔的途径--癌症靶向治疗。此外,生物启发微型机器人已成为一种巧妙的给药方法,可实现癌症治疗的精确性和可控性。这篇主旨综述探讨了脑靶向癌症疗法中错综复杂的神经学洞察力网络,以及生物启发微型机器人的范式转换世界。它对这些不断发展的领域进行了重要而全面的概述,旨在强调它们在革命性癌症治疗方面的整合和潜力。
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来源期刊
Drug Discovery Today
Drug Discovery Today 医学-药学
CiteScore
14.80
自引率
2.70%
发文量
293
审稿时长
6 months
期刊介绍: Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.
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