Biological screening for congenital toxoplasmosis in newborns from Jataí, Goiás, Brazil: a cross-sectional study.

Revista da Escola de Enfermagem da U S P Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI:10.1590/1980-220X-REEUSP-2023-0408en
Gabriela Katrinny Avelar Oliveira, Stéfanne Rodrigues Rezende Ferreira, Vanessa Oliveira Lopes de Moura, Victor da Silva Siqueira, Thaís Santos Anjo Reis, Vanessa Bridi, Ludimila Paula Vaz Cardoso, Hanstter Hallison Alves Rezende
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Abstract

Objective: To conduct a serological screening for toxoplasmosis in the heel prick test and to evaluate its epidemiological aspects in newborns and postpartum women in Jataí, Goiás.

Method: Cross-sectional epidemiological study for the biological screening of newborns in Jataí, Goiás.

Results: The study participants amounted to 228 newborns, whose samples were collected between the third and seventh day of life. IgG antibodies against Toxoplasma gondii were detected in 40.79% (93/228) of the samples; out of these, 23.6% (22/93) had high IgG antibody titers, leading to the collection of two other peripheral blood samples and the detection of a decrease in these titers.

Conclusion: The findings show the importance of strengthening actions in primary health care to prevent infection and training health professionals in this area to equip them with information regarding cases of reinfection and reactivation of infection in pregnant women, minimizing risks for babies.

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巴西戈亚斯州雅塔伊市新生儿先天性弓形虫生物筛查:一项横断面研究。
目的通过足跟点刺试验对弓形虫进行血清学筛查,并对戈亚斯州雅塔伊市新生儿和产后妇女的弓形虫流行病学方面进行评估:方法:对戈亚斯州雅塔伊市的新生儿进行生物学筛查的横断面流行病学研究:参与研究的 228 名新生儿的样本是在出生后第三天至第七天采集的。在 40.79%(93/228)的样本中检测到了弓形虫 IgG 抗体;其中 23.6%(22/93)的样本 IgG 抗体滴度较高,因此采集了另外两个外周血样本,并检测到滴度有所下降:研究结果表明,必须加强初级卫生保健中预防感染的行动,并对该领域的卫生专业人员进行培训,使他们掌握有关孕妇再感染和感染再活化病例的信息,从而最大限度地降低婴儿面临的风险。
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