{"title":"Visible light promoted synthesis of 2-amino sugar analogues from glycals and N-aminopyridinium salts","authors":"","doi":"10.1016/j.tet.2024.134144","DOIUrl":null,"url":null,"abstract":"<div><p>Herin is reported a blue light-promoted (Ir[<em>d</em>F(CF<sub>3</sub>)ppy]<sub>2</sub>(<em>dt</em>bpy))PF<sub>6</sub> catalyzed method that synthesizes the 2-amino sugar analogues from glycals, <em>N</em>-aminopyridinium salts and alcohol. The reactions obtained two diastereomers and the results were not influenced by the kinds of glycals. The advantage of this method is that not only different nitrogen-containing functional groups can be introduced at the C-2 position of the glycals, but also different oxygen-containing functional groups can be attached at C-1 by using methanol, <em>t</em><em>ert</em>-butanol, and water in the reaction.</p></div>","PeriodicalId":437,"journal":{"name":"Tetrahedron","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040402024003247","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Herin is reported a blue light-promoted (Ir[dF(CF3)ppy]2(dtbpy))PF6 catalyzed method that synthesizes the 2-amino sugar analogues from glycals, N-aminopyridinium salts and alcohol. The reactions obtained two diastereomers and the results were not influenced by the kinds of glycals. The advantage of this method is that not only different nitrogen-containing functional groups can be introduced at the C-2 position of the glycals, but also different oxygen-containing functional groups can be attached at C-1 by using methanol, tert-butanol, and water in the reaction.
期刊介绍：
Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry.
Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters.
Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.
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