[Defining the Role of Radiotherapy in Meningioma Treatment].

Q4 Medicine Neurological Surgery Pub Date : 2024-07-01 DOI:10.11477/mf.1436204977
Shinji Kawabata, Hideki Kashiwagi, Naosuke Nonoguchi, Motomasa Furuse, Toshihiro Takami, Shin-Ichi Miyatake, Masahiko Wanibuchi
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引用次数: 0

Abstract

The debate regarding the role and clinical impact of radiotherapy for meningiomas remains underdeveloped due to insufficient evidence. However, following recent revisions in the WHO classification and the integration of molecular diagnostics, there has been a substantial shift in the stratification of recurrence risks. Nevertheless, the specific circumstances under which radiotherapy proves crucial remain unclear. As risk stratification becomes more refined, the effectiveness of radiotherapy in treating high-risk meningiomas continues to be a contentious issue. Concurrently, there is vigorous discussion regarding the management of 'brain invasion in otherwise benign'(BIOB)meningiomas. The incorporation of PET imaging alongside MRI for defining radiation targets is increasingly acknowledged as advantageous. Boron neutron capture therapy(BNCT), which specifically targets the biological characteristics of tumor cells in invasive regions, is also gaining significant traction as a promising therapeutic approach for meningiomas with infiltrative components.

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[确定放疗在脑膜瘤治疗中的作用]。
由于证据不足,有关脑膜瘤放疗的作用和临床影响的讨论仍未充分展开。不过,随着最近世界卫生组织对脑膜瘤分类的修订以及分子诊断技术的应用,对脑膜瘤复发风险的分层有了实质性的改变。然而,放疗在哪些具体情况下起关键作用仍不清楚。随着风险分层的日益完善,放疗对治疗高风险脑膜瘤的有效性仍是一个有争议的问题。与此同时,关于 "良性脑膜瘤中的脑侵犯"(BIOB)的治疗也在激烈讨论中。PET 成像与核磁共振成像(MRI)一起用于确定放射目标的优势日益得到认可。硼中子俘获疗法(BNCT)专门针对浸润区肿瘤细胞的生物特性,作为一种治疗浸润性脑膜瘤的有前途的方法,也正受到越来越多的关注。
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来源期刊
Neurological Surgery
Neurological Surgery Medicine-Medicine (all)
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