Which occurs first, ARID1A inactivation or microsatellite instability?: A comment to Yamamoto et al. (2024)

IF 4.5 2区 医学 Q1 ONCOLOGY Cancer Science Pub Date : 2024-07-21 DOI:10.1111/cas.16294
Dakeun Lee
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Abstract

Is ARID1A a victim of MSI-induced genomic instability, or is it an architect? This article aims to answer from a pathological perspective and give readers a balanced view.

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ARID1A失活和微卫星不稳定哪个先发生?对 Yamamoto 等人(2024 年)的评论。
ARID1A是MSI诱导的基因组不稳定性的受害者,还是设计师?本文旨在从病理学的角度给出答案,为读者提供一个平衡的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer Science
Cancer Science 医学-肿瘤学
自引率
3.50%
发文量
406
审稿时长
2 months
期刊介绍: Cancer Science (formerly Japanese Journal of Cancer Research) is a monthly publication of the Japanese Cancer Association. First published in 1907, the Journal continues to publish original articles, editorials, and letters to the editor, describing original research in the fields of basic, translational and clinical cancer research. The Journal also accepts reports and case reports. Cancer Science aims to present highly significant and timely findings that have a significant clinical impact on oncologists or that may alter the disease concept of a tumor. The Journal will not publish case reports that describe a rare tumor or condition without new findings to be added to previous reports; combination of different tumors without new suggestive findings for oncological research; remarkable effect of already known treatments without suggestive data to explain the exceptional result. Review articles may also be published.
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Issue Information In this issue Issue Information In this issue Real-world genome profiling in Japanese patients with pancreatic ductal adenocarcinoma focusing on HRD implications
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