Systematic review of natural language processing (NLP) applications in magnetic resonance imaging (MRI)

Gazal Mahameed, Dana Brin, Eli Konen, Girish Nadkarni, Eyal Klang
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Abstract

Background: As MRI use grows in medical diagnostics, applying NLP techniques could improve management of related text data. This review aims to explore how NLP can augment radiological evaluations in MRI. Methods: We conducted a PubMed search for studies that applied NLP in the clinical analysis of MRI, including publications up to January 4, 2024. The quality and potential bias of the included studies were assessed using the QUADAS-2 tool. Results: Twenty-six studies published between April 2010 and January 2024, covering more than 160k MRI reports were analyzed. Most of these studies demonstrated low to no risk of bias of the NLP. Neurology was the most frequently studied specialty, with twelve studies, followed by musculoskeletal (MSK) and body imaging. Applications of NLP included staging, quantification, and disease diagnosis. Notably, NLP showed high precision in tumor staging classification and structuring of free-text reports. Conclusion: NLP shows promise in enhancing the utility of MRI. However, there is a need for prospective studies to further validate NLP algorithms in real-time clinical and operational scenarios and across various radiology specialties, which could lead to broader applications in healthcare.
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磁共振成像(MRI)中的自然语言处理(NLP)应用系统综述
背景:随着核磁共振成像技术在医疗诊断中的应用越来越广泛,应用 NLP 技术可以改善相关文本数据的管理。本综述旨在探讨 NLP 如何增强核磁共振成像的放射学评估:我们在 PubMed 上搜索了将 NLP 应用于核磁共振成像临床分析的研究,包括截至 2024 年 1 月 4 日的出版物。我们使用QUADAS-2工具对纳入研究的质量和潜在偏倚进行了评估:结果:分析了 2010 年 4 月至 2024 年 1 月间发表的 26 项研究,涵盖超过 16 万份核磁共振成像报告。其中大部分研究表明,NLP的偏倚风险较低甚至没有。神经病学是研究最多的专业,有12项研究,其次是肌肉骨骼(MSK)和身体成像。NLP 的应用包括分期、量化和疾病诊断。值得注意的是,NLP 在肿瘤分期分类和自由文本报告结构化方面表现出很高的精确度:结论:NLP有望提高核磁共振成像的实用性。然而,还需要进行前瞻性研究,进一步验证 NLP 算法在实时临床和操作场景中以及不同放射专科中的应用,从而在医疗保健领域实现更广泛的应用。
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