Unveiling Multiple Myeloma: Actively Bleeding Extramedullary Gastric Myelomas Lead to Diagnosis.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY ACG Case Reports Journal Pub Date : 2024-07-20 eCollection Date: 2024-07-01 DOI:10.14309/crj.0000000000001449
Katherine Shepherd, George Obeng, Cara Randall, Joanna Kolodney, Megan Willard
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Abstract

Multiple myeloma (MM) is a disease of plasma cell replication, leading to a disruption of hematopoiesis, which commonly presents clinically with anemia and fatigue. Extramedullary myelomas are plasma cell collections in bone or soft tissue associated with MM and most often occur later in the disease process. We present a case of a patient with symptomatic anemia with actively bleeding gastric nodules, which were later found to be extramedullary gastric myelomas when pathology demonstrated kappa-restricted plasma cell neoplasms. To confirm the overall diagnosis, a bone marrow biopsy verified the patient had MM.

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揭开多发性骨髓瘤的神秘面纱:主动出血的髓外胃骨髓瘤导致诊断。
多发性骨髓瘤(MM)是一种浆细胞复制疾病,会导致造血功能紊乱,临床上通常表现为贫血和乏力。髓外骨髓瘤是与骨髓瘤相关的骨或软组织中的浆细胞聚集,通常发生在疾病的后期。我们介绍了一例有症状性贫血并伴有胃结节出血的患者,病理检查显示其为卡帕限制性浆细胞瘤,随后发现其为髓外胃骨髓瘤。为了确诊,骨髓活检证实患者患有骨髓瘤。
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来源期刊
ACG Case Reports Journal
ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-
自引率
14.30%
发文量
170
审稿时长
12 weeks
期刊介绍: ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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