Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review.

IF 3.2 2区医学 Q2 CLINICAL NEUROLOGY Current Pain and Headache Reports Pub Date : 2024-07-23 DOI:10.1007/s11916-024-01277-9

Valeria Giorgi, Piercarlo Sarzi-Puttini, Greta Pellegrino, Silvia Sirotti, Fabiola Atzeni, Alessandra Alciati, Riccardo Torta, Giustino Varrassi, Diego Fornasari, Stefano Coaccioli, Sara Francesca Bongiovanni

{"title":"Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review.","authors":"Valeria Giorgi, Piercarlo Sarzi-Puttini, Greta Pellegrino, Silvia Sirotti, Fabiola Atzeni, Alessandra Alciati, Riccardo Torta, Giustino Varrassi, Diego Fornasari, Stefano Coaccioli, Sara Francesca Bongiovanni","doi":"10.1007/s11916-024-01277-9","DOIUrl":null,"url":null,"abstract":"Purpose of review: Fibromyalgia Syndrome (FMS) is a complex chronic pain condition characterized by widespread musculoskeletal pain and numerous other debilitating symptoms. The purpose of this review is to provide a comprehensive overview, based on everyday clinical practice, of the drugs presently employed in the treatment of FMS.Recent findings: The treatment of FMS is based on a multimodal approach, with pharmacologic treatment being an essential pillar. The drugs used include tricyclic antidepressants, serotonin and noradrenaline reuptake inhibitors, other antidepressants, anticonvulsants, myorelaxants, and analgesics. The effectiveness of these medications varies, and the choice of drug often depends on the specific symptoms presented by the patient. Many drugs tend to either address only some domains of the complex FMS symptomatology or have a limited effect on pain. Each treatment option comes with potential side effects and risks that necessitate careful consideration. It may be beneficial to divide patients into clinical subpopulations, such as FMS with comorbid depression, for more effective treatment. Despite the complexities and challenges, the pharmacological treatment remains a crucial part for the management of FMS. This review aims to guide clinicians in prescribing pharmacological treatment to individuals with FMS.","PeriodicalId":50602,"journal":{"name":"Current Pain and Headache Reports","volume":null,"pages":null},"PeriodicalIF":3.2000,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Pain and Headache Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11916-024-01277-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Fibromyalgia Syndrome (FMS) is a complex chronic pain condition characterized by widespread musculoskeletal pain and numerous other debilitating symptoms. The purpose of this review is to provide a comprehensive overview, based on everyday clinical practice, of the drugs presently employed in the treatment of FMS.

Recent findings: The treatment of FMS is based on a multimodal approach, with pharmacologic treatment being an essential pillar. The drugs used include tricyclic antidepressants, serotonin and noradrenaline reuptake inhibitors, other antidepressants, anticonvulsants, myorelaxants, and analgesics. The effectiveness of these medications varies, and the choice of drug often depends on the specific symptoms presented by the patient. Many drugs tend to either address only some domains of the complex FMS symptomatology or have a limited effect on pain. Each treatment option comes with potential side effects and risks that necessitate careful consideration. It may be beneficial to divide patients into clinical subpopulations, such as FMS with comorbid depression, for more effective treatment. Despite the complexities and challenges, the pharmacological treatment remains a crucial part for the management of FMS. This review aims to guide clinicians in prescribing pharmacological treatment to individuals with FMS.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

纤维肌痛综合征的药物治疗：基于实践的综述。

审查目的：纤维肌痛综合征（FMS）是一种复杂的慢性疼痛病症，其特征是广泛的肌肉骨骼疼痛和许多其他使人衰弱的症状。本综述旨在根据日常临床实践，全面概述目前用于治疗 FMS 的药物：FMS 的治疗以多模式方法为基础，其中药物治疗是必不可少的支柱。使用的药物包括三环类抗抑郁剂、血清素和去甲肾上腺素再摄取抑制剂、其他抗抑郁剂、抗惊厥药、肌松弛药和镇痛药。这些药物的疗效各不相同，药物的选择往往取决于患者的具体症状。许多药物往往只能解决复杂的 FMS 症状的某些方面，或者对疼痛的影响有限。每种治疗方案都有潜在的副作用和风险，需要慎重考虑。将患者划分为不同的临床亚群（如合并抑郁症的 FMS）可能有利于更有效的治疗。尽管存在复杂性和挑战，但药物治疗仍是 FMS 治疗的关键部分。本综述旨在指导临床医生为 FMS 患者开具药物治疗处方。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Pain and Headache Reports CLINICAL NEUROLOGY-

CiteScore

6.10

自引率

2.70%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published clinical findings regarding the diagnosis, treatment, and management of pain and headache. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of pain and headache. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anesthetic techniques in pain management, cluster headache, neuropathic pain, and migraine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.