Greeshma Rajeev-Kumar, Rohan R Katipally, Shen Li, Benjamin D Shogan, Kinga S Olortegui, Janet Chin, Blase N Polite, Stanley L Liauw
{"title":"Point/Counterpoint #2: Current Clinical Considerations With Nonoperative Management of Rectal Cancer.","authors":"Greeshma Rajeev-Kumar, Rohan R Katipally, Shen Li, Benjamin D Shogan, Kinga S Olortegui, Janet Chin, Blase N Polite, Stanley L Liauw","doi":"10.1097/PPO.0000000000000732","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Locally advanced rectal cancer has historically been treated with multimodal therapy consisting of radiation therapy, chemotherapy, and total mesorectal excision. However, recent prospective trials and registry studies have demonstrated similar disease outcomes with nonoperative management for patients who experience an excellent clinical response to radiation and chemotherapy. This article reviews data regarding nonoperative management for rectal cancer, and highlights current challenges and limitations in a point-counterpoint format, in the context of two clinical cases.</p>","PeriodicalId":9655,"journal":{"name":"Cancer journal","volume":"30 4","pages":"256-263"},"PeriodicalIF":2.6000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/PPO.0000000000000732","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Locally advanced rectal cancer has historically been treated with multimodal therapy consisting of radiation therapy, chemotherapy, and total mesorectal excision. However, recent prospective trials and registry studies have demonstrated similar disease outcomes with nonoperative management for patients who experience an excellent clinical response to radiation and chemotherapy. This article reviews data regarding nonoperative management for rectal cancer, and highlights current challenges and limitations in a point-counterpoint format, in the context of two clinical cases.
期刊介绍:
The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.