The efficacy of transcranial random noise stimulation in treating tinnitus: a systematic review.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY European Archives of Oto-Rhino-Laryngology Pub Date : 2024-12-01 Epub Date: 2024-07-24 DOI:10.1007/s00405-024-08858-9

Anas R Alashram

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Abstract

Purpose: This review aims to examine the effects of transcranial random noise stimulation (tRNS) on tinnitus and to determine the optimal treatment parameters, if possible.

Methods: A comprehensive search, including MEDLINE, PubMed, EMBASE, CINAHL, SCOPUS, and PEDro, was conducted to determine experiments studying the effects of tRNS on tinnitus from inception to March 1, 2024. The Physiotherapy Evidence Database (PEDro) scale was used to evaluate the quality of the included studies.

Results: Seven studies met the eligibility criteria. A total of 616 patients with non-pulsatile tinnitus (mean age 50.93 years; 66% males) were included in this review. The included studies ranged from 3 to 8 out of 10 (median = 7) on the PEDro scale. The results showed that tRNS is an effective intervention in reducing tinnitus symptoms.

Conclusions: The evidence for the effects of tRNS on people with chronic non-pulsatile tinnitus is promising. Administering tRNS with an intensity of 1-2 mA, high-frequency (101-650 Hz), using a 35 cm² electrode size over the auditory cortex and DLPFC, for 20 min with eight sessions may demonstrate the desired tRNS effects. The tRNS stimulation should be contralateral for unilateral tinnitus and bilaterally for bilateral tinnitus. Combining tRNS with other concurrent interventions may show superior effects in reducing tinnitus compared to tRNS alone. Further high-quality studies with larger sample sizes are strongly needed.

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经颅随机噪声刺激治疗耳鸣的疗效：系统综述。

目的：本综述旨在研究经颅随机噪声刺激（tRNS）对耳鸣的影响，并在可能的情况下确定最佳治疗参数：方法：我们进行了全面检索，包括MEDLINE、PubMed、EMBASE、CINAHL、SCOPUS和PEDro，以确定从开始到2024年3月1日期间研究经颅随机噪声刺激（tRNS）对耳鸣影响的实验。物理治疗证据数据库（PEDro）量表用于评估纳入研究的质量：结果：七项研究符合资格标准。共有 616 名非搏动性耳鸣患者（平均年龄为 50.93 岁；66% 为男性）被纳入本综述。纳入的研究在 PEDro 量表中的得分从 3 分到 8 分不等（满分 10 分，中位数 = 7 分）。结果显示，tRNS 是减少耳鸣症状的有效干预措施：tRNS对慢性非搏动性耳鸣患者的效果很有希望。在听皮层和 DLPFC 上使用 35 平方厘米大小的电极，以 1-2 mA 的强度、高频（101-650 Hz）进行 tRNS 刺激，持续 20 分钟，共进行八次，可能会产生预期的 tRNS 效果。如果是单侧耳鸣，tRNS 刺激应在对侧进行；如果是双侧耳鸣，则应在双侧进行。与单独使用 tRNS 相比，将 tRNS 与其他同期干预措施相结合可能会在减轻耳鸣方面显示出更佳效果。我们亟需进一步开展样本量更大的高质量研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.