Preliminary differentiation of benign and malignant gastric wall thickening using dual-layer spectral-detector CT.

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Acta radiologica Pub Date : 2024-08-01 Epub Date: 2024-07-25 DOI:10.1177/02841851241260873
Hongjian Li, Qianni Zhu, Linjiang Liu, Haijun Zou, Dayong Gu, Cheng Wu, Weihua Li
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引用次数: 0

Abstract

Background: Dual-layer spectral-detector computed tomography (DLCT) may have the potential to evaluate gastric wall thickening.

Purpose: To evaluate the efficacy of DLCT quantitative parameters in differentiating between benign and malignant thickening of the gastric wall.

Material and methods: A total of 58 patients with "gastric wall thickening" who underwent multi-phase abdominal enhanced DLCT scans were included in this study. Of these patients, 33 were malignant and 25 were benign. Parameters such as iodine concentration (IC), effective atomic number (Zeff), and attenuation of the lesions were measured during the arterial phase (AP) and venous phase (VP). Binary logistic regression was employed to calculate the combined prediction probabilities. The accuracy of the DLCT parameters was assessed using receiver operating characteristic (ROC) curves.

Results: The values of IC, nIC, Zeff, normalized Zeff, and attenuation in the AP and VP were significantly higher (all P < 0.05) in the malignant group compared to the benign group. The ROC curves revealed that the IC, Zeff, and attenuation in the VP exhibited high diagnostic performance, with area under the ROC curve (AUC) values of 0.864, 0.862, and 0.840, respectively. The new combination of these three factors and gastric wall thickness had an AUC of 0.884, and the sensitivity and specificity were determined to be 81.8% and 92.0%, respectively.

Conclusion: Spectral CT parameters, particularly the combination of gastric wall thickness, attenuation, IC, and Zeff in VP, have value in distinguishing between benign and malignant gastric wall thickening.

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使用双层光谱探测器 CT 初步区分良性和恶性胃壁增厚。
背景:目的:评估DLCT定量参数在区分胃壁良性和恶性增厚方面的有效性:本研究共纳入 58 例接受腹部多相增强 DLCT 扫描的 "胃壁增厚 "患者。其中 33 例为恶性,25 例为良性。在动脉期(AP)和静脉期(VP)测量了病变部位的碘浓度(IC)、有效原子序数(Zeff)和衰减等参数。采用二元逻辑回归计算综合预测概率。使用接收器操作特征曲线(ROC)评估 DLCT 参数的准确性:AP期和VP期的IC值、nIC值、Zeff值、归一化Zeff值和衰减值均显著升高(均为P 结论:DLCT参数的准确性与AP期和VP期的预测值密切相关:光谱 CT 参数,尤其是 VP 的胃壁厚度、衰减、IC 和 Zeff 的组合,在区分良性和恶性胃壁增厚方面具有价值。
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来源期刊
Acta radiologica
Acta radiologica 医学-核医学
CiteScore
2.70
自引率
0.00%
发文量
170
审稿时长
3-8 weeks
期刊介绍: Acta Radiologica publishes articles on all aspects of radiology, from clinical radiology to experimental work. It is known for articles based on experimental work and contrast media research, giving priority to scientific original papers. The distinguished international editorial board also invite review articles, short communications and technical and instrumental notes.
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