Liver transplantation for primary liver tumors in pediatrics. A case series.

IF 0.7 4区医学 Q4 PEDIATRICS Archivos argentinos de pediatria Pub Date : 2025-02-01 Epub Date: 2024-08-01 DOI:10.5546/aap.2023-10222.eng

Erika M Selzer Soria, Ariel González Campaña, Alejandro Siaba Serrate, Mariana Varela, Cecilia Lagues, Martín Fauda, Ivone Malla

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Abstract

Primary liver tumors are an increasing indication for pediatric liver transplantation. Here we report the cases of 10 patients who underwent liver transplantation for primary liver tumors in our hospital, from 2001 to date. Up to 2011, 1 transplant due to hepatoblastoma was done out of 117 liver transplants (0.8%). Since 2012, there were 9 patients out of 141 (6.4%) (5 due to hepatoblastoma, 2 due to hepatocellular carcinoma, 1 due to hepatic epithelioid hemangioendothelioma, and 1 due to hepatic mesenchymal hamartoma). Follow-up: 13.2 months (median); age at transplantation: living 4.7 years (median); weight: 17.6 kg (median). Eighty percent of patients received grafts from living donors. No tumor recurrence was observed. Survival was 100% in the follow-up period. In our series, patients with primary liver tumors requiring transplantation showed an adequate course, even in the case of hepatocellular carcinoma, Related living donors liver transplantation shortened the time between the indication and the surgery.

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儿科原发性肝肿瘤的肝移植。病例系列。

原发性肝肿瘤是越来越多小儿肝移植的适应症。在此，我们报告了本院自2001年至今因原发性肝肿瘤接受肝移植的10例患者的病例。截至2011年，在117例肝移植中，有1例因肝母细胞瘤进行了肝移植（0.8%）。2012 年以来，141 例肝移植中有 9 例（6.4%）患者（5 例为肝母细胞瘤，2 例为肝细胞癌，1 例为肝上皮样血管内皮瘤，1 例为肝间质火腿肠瘤）。随访时间：13.2 个月（中位数）；移植年龄：4.7 岁（中位数）；体重：17.6 千克（中位数）。80%的患者接受了活体移植。未发现肿瘤复发。随访期间的存活率为100%。在我们的系列研究中，即使是肝细胞癌患者，需要移植的原发性肝脏肿瘤患者的病程也很充分，相关的活体肝移植缩短了从适应症到手术的时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archivos argentinos de pediatria PEDIATRICS-

CiteScore

1.40

自引率

25.00%

发文量

286

审稿时长

6-12 weeks

期刊介绍： Archivos Argentinos de Pediatría is the official publication of the Sociedad Argentina de Pediatría (SAP) and has been published without interruption since 1930. Its publication is bimonthly. Archivos Argentinos de Pediatría publishes articles related to perinatal, child and adolescent health and other relevant disciplines for the medical profession.

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