Associations Between Tinnitus and Systemic Disease in Adolescents: Implications of Vitamin D Deficiency and Anaemia

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY Clinical Otolaryngology Pub Date : 2024-07-24 DOI:10.1111/coa.14203

Sang-Yoon Han, Young Ho Kim

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Abstract

Objectives

Tinnitus is one of the irritating symptoms that should be addressed in adolescents. Since tinnitus affects mental health, it is important to treat it. However, identifying the cause of tinnitus is very challenging and the treatment strategies of tinnitus are controversial. The objective of this study was to identify the prevalence of tinnitus in adolescents and systemic diseases as risk factors of adolescent tinnitus to find evidence for new treatment strategies.

Materials and Methods

We extracted the subjects and data using the 5th Korea National Health and Nutrition Examination Survey from 2010 to 2012. One thousand five hundred ninety-three adolescents with bilateral normal tympanic membranes and availability of the results of physical, laboratory and audiological examinations, were selected. We evaluated their systemic diseases based on these results and assessed the association of tinnitus with demographic factors, systemic diseases and hearing levels.

Results

The prevalence of tinnitus in Korean adolescents was 21.7%. The hearing level was not associated with tinnitus. Tinnitus was significantly associated with age (p = 0.005), 25(OH)-D level (p = 0.007) and anaemia (p = 0.003). After controlling the other factors, age (p = 0.045), 25(OH)-D level (p = 0.041) and anaemia (p = 0.019) were independently related to tinnitus.

Conclusion

Tinnitus in adolescents was significantly associated with age, vitamin D and anaemia. Physicians should consider the higher likelihood of these deficiencies or diseases in adolescent tinnitus patients. Additionally, recognizing these associations may be helpful in developing treatment strategies for adolescent tinnitus.

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青少年耳鸣与全身性疾病的关系：维生素 D 缺乏和贫血的影响。

目的：耳鸣是青少年应注意的刺激性症状之一。由于耳鸣会影响心理健康，因此治疗耳鸣非常重要。然而，确定耳鸣的原因非常具有挑战性，耳鸣的治疗策略也存在争议。本研究旨在确定青少年耳鸣的发病率以及作为青少年耳鸣风险因素的系统性疾病，从而为新的治疗策略寻找证据：我们通过2010年至2012年的第五次韩国国民健康与营养调查提取了研究对象和数据。我们选取了 1 593 名双侧鼓膜正常且有体格检查、实验室检查和听力检查结果的青少年。我们根据这些结果评估了他们的全身性疾病，并评估了耳鸣与人口统计学因素、全身性疾病和听力水平的关系：结果：韩国青少年耳鸣的发病率为 21.7%。听力水平与耳鸣无关。耳鸣与年龄（p = 0.005）、25（OH）-D 水平（p = 0.007）和贫血（p = 0.003）明显相关。在控制了其他因素后，年龄（p = 0.045）、25（OH）-D 水平（p = 0.041）和贫血（p = 0.019）与耳鸣独立相关：结论：青少年耳鸣与年龄、维生素 D 和贫血密切相关。结论：青少年耳鸣与年龄、维生素 D 和贫血密切相关，医生应考虑到青少年耳鸣患者更有可能缺乏维生素 D 或患有这些疾病。此外，认识到这些关联可能有助于为青少年耳鸣制定治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.