Sulaiman S Alsaif, Wendy Douglas, Joerg Steier, Mary J Morrell, Michael I Polkey, Julia L Kelly
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引用次数: 0
Abstract
Many patients with obstructive sleep apnoea (OSA) remain undiagnosed and thus untreated, and in part this relates to delay in diagnosis. Novel diagnostic strategies may improve access to diagnosis. In a multicentre, randomised study, we evaluated time to treatment decision in patients referred for suspected OSA, comparing a mandibular movement (MM) monitor to respiratory polygraphy, the most commonly used OSA detection method in the UK. Adults with high pre-test probability OSA were recruited from both northern Scotland and London. 40 participants (70 % male, mean±SD age 46.8 ± 12.9 years, BMI 36.9 ± 7.5 kg/m2, ESS 14.9 ± 4.1) wore a MM monitor and respiratory polygraphy simultaneously overnight and were randomised (1:1) to receive their treatment decision based on results from either device. Compared to respiratory polygraphy, MM monitor reduced time to treatment decision by 6 days (median(IQR): 13.5 (7.0-21.5) vs. 19.5 (13.7-35.5) days, P = 0.017) and saved an estimated 29 min of staff time per patient.
许多阻塞性睡眠呼吸暂停(OSA)患者仍未得到诊断,因此也未得到治疗,这在一定程度上与诊断延误有关。新的诊断策略可能会提高诊断率。在一项多中心随机研究中,我们对因疑似 OSA 而转诊的患者做出治疗决定所需的时间进行了评估,并将下颌骨运动(MM)监测仪与呼吸测谎仪(英国最常用的 OSA 检测方法)进行了比较。我们从苏格兰北部和伦敦招募了测试前可能性较高的 OSA 成人。40名参与者(70%为男性,平均年龄(±SD)为46.8±12.9岁,体重指数(BMI)为36.9±7.5 kg/m2,ESS为14.9±4.1)同时佩戴MM监测仪和呼吸测谎仪过夜,并随机(1:1)根据任一设备的结果决定是否接受治疗。与呼吸测谎仪相比,MM 监测仪将做出治疗决定的时间缩短了 6 天(中位数(IQR):13.5(7.0-21.5) vs. 19.5(13.7-35.5),P=0.017),并为每位患者节省了约 29 分钟的工作人员时间。
期刊介绍:
Clinical Medicine is aimed at practising physicians in the UK and overseas and has relevance to all those managing or working within the healthcare sector.
Available in print and online, the journal seeks to encourage high standards of medical care by promoting good clinical practice through original research, review and comment. The journal also includes a dedicated continuing medical education (CME) section in each issue. This presents the latest advances in a chosen specialty, with self-assessment questions at the end of each topic enabling CPD accreditation to be acquired.
ISSN: 1470-2118 E-ISSN: 1473-4893 Frequency: 6 issues per year