A Case study of polypharmacy-induced serotonin syndrome in a cancer patient.

Andrew Zhu, Nicole Kuhnly, Leon Chen, Alina O Dulu
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Abstract

Abstract: Polypharmacy in cancer care can be complex and detrimental, particularly among younger patients, who can be easily overlooked. This report showcases a 54-year-old woman with cancer, treated for dapsone-induced methemoglobinemia with methylene blue (MB), subsequently developing serotonin syndrome (SS) due to concurrent serotonin-active medications. This case highlights the critical impact of polypharmacy, emphasizing the necessity for acute care providers to diligently assess medication interactions, especially in emergencies. It underscores the importance of considering alternative treatments and the vigilant monitoring of symptoms indicative of adverse drug interactions to ensure patient safety and optimize outcomes in complex therapeutic scenarios.

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癌症患者多药诱发血清素综合征的病例研究。
摘要:癌症护理中的多重用药可能既复杂又有害,尤其是年轻患者,他们很容易被忽视。本报告介绍了一名 54 岁的癌症女性患者,她因使用亚甲蓝(MB)治疗地塞米松诱发的高铁血红蛋白血症,随后因同时服用血清素活性药物而患上血清素综合征(SS)。本病例突出了多种药物治疗的重要影响,强调了急诊医疗服务提供者认真评估药物相互作用的必要性,尤其是在紧急情况下。它强调了在复杂的治疗情况下,考虑替代疗法和警惕监测药物不良相互作用的症状以确保患者安全和优化治疗效果的重要性。
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来源期刊
自引率
16.70%
发文量
172
期刊介绍: The Journal of the American Association of Nurse Practitioners (JAANP) is a monthly peer-reviewed professional journal that serves as the official publication of the American Association of Nurse Practitioners. Published since 1989, the JAANP provides a strong clinical focus with articles related to primary, secondary, and tertiary care, nurse practitioner education, health policy, ethics and ethical issues, and health care delivery. The journal publishes original research, integrative/comprehensive reviews, case studies, a variety of topics in clinical practice, and theory-based articles related to patient and professional education. Although the majority of nurse practitioners function in primary care, there is an increasing focus on the provision of care across all types of systems from acute to long-term care settings.
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