Efficacy, Confounders and Safety of the Preserflo Microshunt.

IF 0.8 4区医学 Q4 OPHTHALMOLOGY Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-09-01 Epub Date: 2024-07-24 DOI:10.1055/a-2325-9286

Cemre Altas, Thomas A Fuchsluger, Tobias Brockmann, Anna Graumüller, Marcus Walckling

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Abstract

Background: Glaucoma is a leading cause of blindness worldwide. We evaluated the efficacy, confounders, and safety of the Preserflo Microshunt over a one-year follow-up period.

Methods: In this retrospective monocentric study, 111 eyes were evaluated. 83 eyes had primary open angle glaucoma, and 28 eyes secondary open angle glaucoma. Intraocular pressure (IOP), visual acuity, number of glaucoma medications, complications, and reoperations were evaluated postoperatively, at 1, 3, 6, 9, and 12 months. The influence of age, sex, type of glaucoma, previous surgery and lens status was also analysed. Bleb revision was indicated if corrected IOP exceeded 18 mmHg.

Results: Intraocular pressure significantly decreased from 24.50 ± 8.94 to 14.62 ± 4.86 mmHg (4 - 32 mmHg; p < 0.001), the number of medications from 3.19 ± 1.14 to 0.98 ± 1.39 (0 - 4; p < 0.001). Confounders of interest did not affect efficacy. Bleb revision was performed in 22.5% of eyes and a cyclophotocoagulation was performed in 9.9% of eyes. Complete surgical success (IOP ≤ 17 mmHg, IOP reduction ≥ 20%, without medication) was achieved in 36.9% (n = 41) and qualified success (with medication) in 51.4% (n = 57) of eyes. Transient hypotension (≤ 5 mmHg) occurred in 19.8% after primary implantation and in 1.8% after bleb revision (duration ≤ 3 months).

Conclusion: To date, the Preserflo Microshunt has demonstrated good efficacy and a low risk profile.

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Preserflo 微分流术的疗效、并发症和安全性

背景：青光眼是全球致盲的主要原因。我们对 Preserflo 微分流术一年随访期的疗效、混杂因素和安全性进行了评估：在这项回顾性单中心研究中，我们对 111 只眼睛进行了评估。83只眼睛患有原发性开角型青光眼，28只眼睛患有继发性开角型青光眼。术后1、3、6、9和12个月对眼压（IOP）、视力、青光眼用药次数、并发症和再次手术进行了评估。此外，还分析了年龄、性别、青光眼类型、既往手术和晶状体状态的影响。如果矫正后的眼压超过 18 mmHg，则需要进行眼压计修整：结果：眼内压从 24.50 ± 8.94 mmHg 显著下降到 14.62 ± 4.86 mmHg（4 - 32 mmHg；p 结论：Preserfloor 技术是目前最有效的青光眼治疗方法：迄今为止，Preserflo 微分流术已证明疗效好、风险低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Klinische Monatsblatter fur Augenheilkunde 医学-眼科学

CiteScore

1.30

自引率

0.00%

发文量

235

审稿时长

4-8 weeks

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