Guardian's knowledge and attitude towards inhaled corticosteroids aerosol therapy and medication compliance of children with wheezing diseases.

IF 2.6 4区 医学 Q2 ALLERGY Allergy Asthma and Clinical Immunology Pub Date : 2024-07-24 DOI:10.1186/s13223-024-00908-5
Zuojiao Liu, Haiqing Dai, Fengjiao Tao, Xiaoxiao He, Ting Jin
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引用次数: 0

Abstract

Background: Glucocorticoids are widely used in inhalation aerosol therapy for wheezing diseases. This study aims to explore guardians' knowledge and attitude towards inhaled corticosteroids (ICS) aerosol therapy and the medication compliance of children with wheezing diseases in China.

Methods: This cross-sectional study enrolled guardians of children with wheezing diseases at the First Hospital Affiliated to Shaoyang College between October 2022 and February 2023. A self-administered questionnaire was developed to collect demographic information of the participants and evaluate their knowledge and attitude towards ICS aerosol therapy. The 8-item Morisky Medication Adherence Scale was used to assess the medication compliance of children.

Results: A total of 506 valid questionnaires were collected. 260 (51.38%) participants were guardians of a ≤ 3-year-old child and 327 (64.62%) were children's mothers. The knowledge, attitude, and medication compliance scores of all participants were 12.61 ± 5.78, 20.95 ± 2.37, and 4.69 ± 2.18, respectively. Multivariate logistic regression showed that knowledge scores [OR = 1.053, 95% CI (confidence interval): 1.017-1.090, P = 0.003], attitude scores (OR = 1.121, 95% CI: 1.030-1.219, P = 0.008), guardians of children aged 4-6 years (OR = 0.385, 95% CI: 0.242-0.612, P < 0.001), and grandparents of children (OR = 2.633, 95% CI: 1.104-6.275, P = 0.029) were independently associated with children's medication compliance.

Conclusions: In conclusion, guardians of children with wheezing diseases in China had insufficient knowledge, unsatisfactory attitude, and poor medication compliance towards ICS aerosol therapy.

Trial registration: Retrospectively registered.

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监护人对吸入式皮质类固醇气雾剂疗法的认识和态度以及喘息病患儿的用药依从性。
背景:糖皮质激素被广泛用于喘息性疾病的吸入气雾剂治疗。本研究旨在探讨中国监护人对吸入性糖皮质激素(ICS)气雾剂治疗的认识和态度,以及喘息病患儿的用药依从性:本横断面研究招募了2022年10月至2023年2月期间在邵阳学院附属第一医院就诊的喘息病患儿的监护人。本研究采用自填式问卷调查法收集受试者的人口统计学信息,并评估其对 ICS 气雾剂治疗的认知和态度。采用8项莫里斯基用药依从性量表评估儿童的用药依从性:共收集到 506 份有效问卷。其中 260 人(51.38%)为 3 岁以下儿童的监护人,327 人(64.62%)为儿童的母亲。所有参与者的知识、态度和用药依从性得分分别为(12.61 ± 5.78)、(20.95 ± 2.37)和(4.69 ± 2.18)。多变量逻辑回归结果显示,知识得分[OR = 1.053,95% CI(置信区间):1.017-1.090,P = 0.003]、态度得分(OR = 1.121,95% CI:1.030-1.219,P = 0.008)、4-6 岁儿童监护人(OR = 0.385,95% CI:0.242-0.612,P 结论:儿童监护人对药物依从性的了解程度越高,对药物依从性的了解程度越低:总之,中国喘息性疾病患儿的监护人对ICS气雾剂治疗的认识不足、态度不佳、用药依从性差:试验注册:回顾性注册。
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来源期刊
CiteScore
4.30
自引率
3.70%
发文量
96
审稿时长
12 weeks
期刊介绍: Allergy, Asthma & Clinical Immunology (AACI), the official journal of the Canadian Society of Allergy and Clinical Immunology (CSACI), is an open access journal that encompasses all aspects of diagnosis, epidemiology, prevention and treatment of allergic and immunologic disease. By offering a high-visibility forum for new insights and discussions, AACI provides a platform for the dissemination of allergy and clinical immunology research and reviews amongst allergists, pulmonologists, immunologists and other physicians, healthcare workers, medical students and the public worldwide. AACI reports on basic research and clinically applied studies in the following areas and other related topics: asthma and occupational lung disease, rhinoconjunctivitis and rhinosinusitis, drug hypersensitivity, allergic skin diseases, urticaria and angioedema, venom hypersensitivity, anaphylaxis and food allergy, immunotherapy, immune modulators and biologics, immune deficiency and autoimmunity, T cell and B cell functions, regulatory T cells, natural killer cells, mast cell and eosinophil functions, complement abnormalities.
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