{"title":"A perspective on brain-age estimation and its clinical promise","authors":"Christian Gaser, Polona Kalc, James H. Cole","doi":"10.1038/s43588-024-00659-8","DOIUrl":null,"url":null,"abstract":"Brain-age estimation has gained increased attention in the neuroscientific community owing to its potential use as a biomarker of brain health. The difference between estimated and chronological age based on neuroimaging data enables a unique perspective on brain development and aging, with multiple open questions still remaining in the brain-age research field. This Perspective presents an overview of current advancements in the field and envisions the future evolution of the brain-age framework before its potential deployment in hospital settings. Brain-age estimation is gaining attention as a biomarker for brain health as it provides a unique perspective on aging. This Perspective reviews current advancements and future directions to ensure deployment in hospital settings.","PeriodicalId":74246,"journal":{"name":"Nature computational science","volume":"4 10","pages":"744-751"},"PeriodicalIF":12.0000,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature computational science","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43588-024-00659-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Brain-age estimation has gained increased attention in the neuroscientific community owing to its potential use as a biomarker of brain health. The difference between estimated and chronological age based on neuroimaging data enables a unique perspective on brain development and aging, with multiple open questions still remaining in the brain-age research field. This Perspective presents an overview of current advancements in the field and envisions the future evolution of the brain-age framework before its potential deployment in hospital settings. Brain-age estimation is gaining attention as a biomarker for brain health as it provides a unique perspective on aging. This Perspective reviews current advancements and future directions to ensure deployment in hospital settings.