A practice already in use: a snapshot survey on the use of doxycycline as a preventive strategy (Doxy-PEP and Doxy-PrEP) in the GBMSM population in Spain.

IF 5.4 2区 医学 Q1 INFECTIOUS DISEASES Infection Pub Date : 2025-02-01 Epub Date: 2024-07-25 DOI:10.1007/s15010-024-02320-y
Villanueva Baselga Sergio, Mora Ruben, Villegas Luis
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引用次数: 0

Abstract

Purpose: . While doxycycline shows promise as a preventative measure against certain STIs (post-exposure prophylaxis or PEP, and pre-exposure prophylaxis or PrEP), very few medical and scientific associations favor its community use. Nevertheless, sexual health organizations for gay, bisexual and other men who have sex with men (GBMSM) community have noticed an increase in requests of its use.

Methods: . The sexual health organization "Stop Sida" in Spain launched an anonymous snapshot survey to evaluate the current use of doxycycline as prevention strategy (both PEP and PrEP) in Spain through its social networks and its support groups in telegram.

Results: . 150 valid answers were obtained from different parts of Spain. 82 respondents (54,6% of total) had ever taken doxycycline, out of which 29 (35,4%) indicated the use as doxy-PEP and 7 (8,5%) as doxy-PrEP. The self-reported rate of STI diagnoses (mainly of syphilis and chlamydia) in the past 12 months was lower among those participants who reported having used doxy-PEP compared with those who did not report using doxy-PEP. The most common ways to obtain the doxycycline were telling a specialist that they have had a risky contact or by using leftover pills from a previous treatment.

Conclusion: The current study is the first study to describe the use of doxycycline as a preventive strategy among the GBMSM community in Spain, and the first designed, launched and analyzed entirely by an NGO dealing with sexual health for the GBMSM community. The results obtained are aligned with other studies in other parts of Europe, such as Germany.

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已在使用的做法:关于在西班牙将强力霉素作为一种预防性策略(Doxy-PEP 和 Doxy-PrEP)在 GBMSM 群体中使用情况的简要调查。
目的:.虽然强力霉素有望成为预防某些性传播感染的措施(暴露后预防或 PEP 和暴露前预防或 PrEP),但很少有医学和科学协会支持在社区使用该药物。不过,男同性恋、双性恋和其他男男性行为者(GBMSM)群体的性健康组织已经注意到,要求使用这种药物的人越来越多。西班牙性健康组织 "Stop Sida "通过其社交网络和电报支持小组发起了一项匿名快照调查,以评估西班牙目前使用强力霉素作为预防策略(PEP 和 PrEP)的情况。从西班牙不同地区获得了 150 份有效答案。82名受访者(占总数的54.6%)曾经服用过多西环素,其中29人(占35.4%)表示将其作为多西环素PEP使用,7人(占8.5%)表示将其作为多西环素PrEP使用。与未报告使用过强力霉素-PEP 的参与者相比,报告使用过强力霉素-PEP 的参与者在过去 12 个月中自我报告的性传播感染(主要是梅毒和衣原体)诊断率较低。获得强力霉素的最常见途径是告诉专科医生他们曾有过危险接触,或使用以前治疗后剩下的药片:本研究是第一项描述在西班牙同性恋、双性恋和变性者群体中使用强力霉素作为预防策略的研究,也是第一项完全由从事同性恋、双性恋和变性者群体性健康工作的非政府组织设计、发起和分析的研究。研究结果与欧洲其他地区(如德国)的其他研究结果一致。
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来源期刊
Infection
Infection 医学-传染病学
CiteScore
12.50
自引率
1.30%
发文量
224
审稿时长
6-12 weeks
期刊介绍: Infection is a journal dedicated to serving as a global forum for the presentation and discussion of clinically relevant information on infectious diseases. Its primary goal is to engage readers and contributors from various regions around the world in the exchange of knowledge about the etiology, pathogenesis, diagnosis, and treatment of infectious diseases, both in outpatient and inpatient settings. The journal covers a wide range of topics, including: Etiology: The study of the causes of infectious diseases. Pathogenesis: The process by which an infectious agent causes disease. Diagnosis: The methods and techniques used to identify infectious diseases. Treatment: The medical interventions and strategies employed to treat infectious diseases. Public Health: Issues of local, regional, or international significance related to infectious diseases, including prevention, control, and management strategies. Hospital Epidemiology: The study of the spread of infectious diseases within healthcare settings and the measures to prevent nosocomial infections. In addition to these, Infection also includes a specialized "Images" section, which focuses on high-quality visual content, such as images, photographs, and microscopic slides, accompanied by brief abstracts. This section is designed to highlight the clinical and diagnostic value of visual aids in the field of infectious diseases, as many conditions present with characteristic clinical signs that can be diagnosed through inspection, and imaging and microscopy are crucial for accurate diagnosis. The journal's comprehensive approach ensures that it remains a valuable resource for healthcare professionals and researchers in the field of infectious diseases.
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