Current and Emerging Approaches for Primary Prevention of Coronary Artery Disease Using Cardiac Computed Tomography

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Cardiology Reports Pub Date : 2024-07-27 DOI:10.1007/s11886-024-02104-8

Polydoros N. Kampaktsis, Carolyn Hennecken, Mrinali Shetty, Laura McLaughlin, Georgios Rampidis, Athanasios Samaras, Dimitrios Avgerinos, Nikolaos Spilias, Toshiki Kuno, Alexandros Briasoulis, Andrew J. Einstein

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Abstract

Purpose of Review

To summarize the current use of cardiac computed tomography (CT) technologies as well as their pertinent evidence in regards to prevention of coronary artery disease (CAD).

Recent Findings

Cardiac CTA has now become a main non-invasive method for the evaluation of symptomatic CAD. In addition to coronary calcium score, other CT technologies such as atherosclerotic plaque analysis, fractional flow reserve estimation by CT, pericoronary fat attenuation, and endothelial wall shear stress have emerged. Whether the use of CT modalities can enhance risk prediction and prevention in CAD has not been fully answered.

Summary

We discuss the evidence for coronary artery calcium scoring and coronary CT angiography in primary prevention and the current barriers to their use. We attempt to delineate what can be done to expand use and what studies are needed to broaden adoption in the future. We also examine the potential roles of emerging CT technologies. Finally, we describe potential clinical approaches to prevention that would incorporate cardiac CT technologies.

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使用心脏计算机断层扫描进行冠状动脉疾病一级预防的现有方法和新方法

综述目的总结当前心脏计算机断层扫描（CT）技术的使用情况及其在预防冠状动脉疾病（CAD）方面的相关证据。除冠状动脉钙化评分外，还出现了其他 CT 技术，如动脉粥样硬化斑块分析、CT 分数血流储备评估、冠状动脉周围脂肪衰减和内皮壁剪切应力。摘要我们讨论了冠状动脉钙化评分和冠状动脉 CT 血管造影术在一级预防中的应用证据以及目前的应用障碍。我们试图说明可采取哪些措施来扩大使用范围，以及未来需要开展哪些研究来扩大使用范围。我们还研究了新兴 CT 技术的潜在作用。最后，我们介绍了结合心脏 CT 技术的潜在临床预防方法。

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来源期刊

Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.20

自引率

2.70%

发文量

209

期刊介绍： The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.