Yashaswini Singh, Adarsh Chandra Mishra, Sapana Yadav, Laxmi Jaiswal, Pooja Lohia, D. K. Dwivedi, R. K. Yadav, Gaber E. Eldesoky, M. Khalid Hossain
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引用次数: 0
Abstract
A highly sensitive hybrid structure for biosensing application based on surface plasmon resonance for the detection of blood cancer has been proposed in this article. The biosensor comprises of a CaF2 Prism, Ag metal, an oxide layer Al2O3 and a 2D nanomaterial graphene, which is grounded on Kretschmann configuration. The transfer matrix method is used to interrogate the performance parameters of proposed biosensor. To analyze the change in refractive index, the analyte has been considered over the graphene layer. To achieve maximum sensitivity and minimum reflectance the thickness of Ag, Al2O3 layers and number of graphene layers have been optimized. The suggested structure’s sensitivity can be enhanced up to 427.43 deg/RIU with the optimized value for the detection accuracy and FOM of 0.7027 deg−1 and 217 RIU−1 respectively. The work focuses on the development of plasmonic sensors with high performance and stability. Role of different material layers is also analyzed in terms of enhancement in sensitivity and evanescent field. The paper offers better optimization technique and selection of material than previously reported works, which eventually leads to enhancement in both sensitivity and FOM. This research could lead to the development of a useful biological sample sensing tool for the quick and precise detection of the blood cancer in its early stages.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.