Comparison between indocyanine green angiography and optical coherence tomography angiography for the detection of nonexudative macular neovascularization

Graefe's Archive for Clinical and Experimental Ophthalmology Pub Date : 2024-07-27 DOI:10.1007/s00417-024-06597-5

Stefan Kickinger, Martin Stattin, Anna-Maria Haas, Daniel Ahmed-Balestra, Michael Jacob, Claus Zehetner, Katharina Krepler, Siamak Ansari-Shahrezaei

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Abstract

What is known

•The prevalence of nonexudative MNV (neMNV) in the opposite eyes of patients with unilateral exudative neovascular AMD (nAMD) ranges from 6 to 27%. The importance of screening and in consequence close monitoring of a detected neMNV is underlined by the 14 to 23-fold risk of conversion to exudative disease, which they carry within the first two years of follow up.

•In the only study designed to compare the sensitivity of OCTA vs. ICGA, 3/41 eyes exhibited neMNV in both modalities and were therefore equally effective.

What is new

•This study showed that in a larger study population of 241 patients the sensitivity of ICGA and OCTA were equal with 80% (32/40) and 83% (33/40), although some neMNV would be missed by solely employing one imaging method.

•Accurate detection of neMNV using multimodal imaging should result in better monitoring of patients who are at high risk of conversion to exudative nAMD.

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吲哚青绿血管造影术与光学相干断层血管造影术在检测非渗出性黄斑新生血管方面的比较

已知情况 -单侧渗出性新生血管性黄斑病变（nAMD）患者对侧眼非渗出性新生血管性视网膜病变（neMNV）的发病率为 6% 至 27%。在最初两年的随访中，非渗出性新生血管性视网膜病变患者转为渗出性疾病的风险高达 14 至 23 倍，这突出表明了筛查和密切监测已发现的新生血管性视网膜病变的重要性。-这项研究表明，在一个由 241 名患者组成的更大的研究群体中，ICGA 和 OCTA 的灵敏度相当，分别为 80%（32/40）和 83%（33/40），尽管仅使用一种成像方法会漏掉一些新生血管。-使用多模态成像技术准确检测新MNV，应能更好地监测有高风险转为渗出性nAMD的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Graefe's Archive for Clinical and Experimental Ophthalmology

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