Advanced Terahertz Waveguide Biosensing: Blood Component Detection with a Pentagonal Cladding and Decagonal Core Fiber Design

IF 1.5 4区 物理与天体物理 Q2 PHYSICS, MULTIDISCIPLINARY Brazilian Journal of Physics Pub Date : 2024-07-26 DOI:10.1007/s13538-024-01560-5
A. H. M. Iftekharul Ferdous, Sakhawat Hossain, Perumal Kalpana Devi, Aranganathan Anandan, Benjir Newaz Sathi, Khalid Sifulla Noor, Md.Sabbir Hossain, Kayab Khandakar, Ahmed Nabih Zaki Rashed, Mahmoud M. A. Eid
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Abstract

An optical sensor that recognizes various blood constituent types is demonstrated in this work and is based on a pentagonal-shaped cladding photonic crystal fiber (PCF) model with a decagonal core. The terahertz frequency, which spans from 1.2 to 3 THz, has been examined with the goal of improving relative sensitivity with minimal confinement loss. COMSOL Multiphysics software is used to analyze the sensor’s sensing and guiding properties through an implementation of the finite element method (FEM) technique. Regarding the chosen analytes, comprising red blood cells (RBCs), hemoglobin (HB), white blood cells (WBCs), plasma, and water, notable relative sensitivity responses of 97.26%, 96.52%, 95.62%, 95.08%, and 93.84% are attained at a frequency of 2.2 THz. In order the same analytes and THz frequency in y-polarization mode, small confinement loss (CL) of 2.92 × 10−11 dB/m and effective material loss (EML) of 0.0052 cm−1 are also acquired respectively. All of these typical values for the optical characteristics show the biosensor’s potential because they assure higher sensitivity for detecting blood components while minimizing confinement and material loss.

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先进的太赫兹波导生物传感技术:利用五边形包层和十边形芯光纤设计检测血液成分
这项研究展示了一种可识别各种血液成分类型的光学传感器,它基于一个具有十边形纤芯的五边形包层光子晶体光纤(PCF)模型。我们对 1.2 至 3 太赫兹的太赫兹频率进行了研究,目的是提高相对灵敏度,同时尽量减少封闭损耗。COMSOL Multiphysics 软件通过有限元法 (FEM) 技术分析了传感器的传感和导向特性。对于所选的分析物,包括红细胞 (RBC)、血红蛋白 (HB)、白细胞 (WBC)、血浆和水,在 2.2 THz 频率下的相对灵敏度响应分别为 97.26%、96.52%、95.62%、95.08% 和 93.84%。在 y 极化模式下,针对相同的分析物和太赫兹频率,还分别获得了 2.92 × 10-11 dB/m 的小约束损耗 (CL) 和 0.0052 cm-1 的有效材料损耗 (EML)。所有这些光学特性的典型值都显示了生物传感器的潜力,因为它们能确保在检测血液成分时具有更高的灵敏度,同时最大限度地减少约束和材料损耗。
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来源期刊
Brazilian Journal of Physics
Brazilian Journal of Physics 物理-物理:综合
CiteScore
2.50
自引率
6.20%
发文量
189
审稿时长
6.0 months
期刊介绍: The Brazilian Journal of Physics is a peer-reviewed international journal published by the Brazilian Physical Society (SBF). The journal publishes new and original research results from all areas of physics, obtained in Brazil and from anywhere else in the world. Contents include theoretical, practical and experimental papers as well as high-quality review papers. Submissions should follow the generally accepted structure for journal articles with basic elements: title, abstract, introduction, results, conclusions, and references.
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