Design and Analysis of a Terahertz Metasurface-Based Refractive Index Sensor for Hemoglobin Detection With Behaviour Prediction Using Polynomial Regression
Jacob Wekalao, Ngaira Mandela, Jonas Muheki, Adeeb Zaid
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引用次数: 0
Abstract
This study presents the design and analysis of a novel terahertz metasurface-based refractive index sensor for hemoglobin detection. The proposed sensor incorporates advanced materials including graphene, MXenes, SrTiO3 and gold on a SiO2 substrate. Comprehensive parametric optimization was conducted using COMSOL Multiphysics to enhance the sensor's sensitivity and overall performance. The optimized design demonstrated high sensitivity to hemoglobin concentration changes, with distinct transmittance responses observed for concentrations ranging from 10 g/l to 40 g/l. Electric field intensity analysis verified the sensor's transmission characteristics across different frequencies. Performance metrics such maximum sensitivity of 1000GHzRIU-1, minimum FOM of 2 RIU-1, minimum detection limit of 0.044 among other performance parameters which demonstrates exemplary results. Furthermore, polynomial regression models were employed to predict the sensor's behaviour under various parametric conditions, achieving maximum R2 scores between 0.86 and 1 across different test cases.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.