Design and Analysis of a Terahertz Metasurface-Based Refractive Index Sensor for Hemoglobin Detection With Behaviour Prediction Using Polynomial Regression

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL Plasmonics Pub Date : 2024-07-27 DOI:10.1007/s11468-024-02445-8
Jacob Wekalao, Ngaira Mandela, Jonas Muheki, Adeeb Zaid
{"title":"Design and Analysis of a Terahertz Metasurface-Based Refractive Index Sensor for Hemoglobin Detection With Behaviour Prediction Using Polynomial Regression","authors":"Jacob Wekalao, Ngaira Mandela, Jonas Muheki, Adeeb Zaid","doi":"10.1007/s11468-024-02445-8","DOIUrl":null,"url":null,"abstract":"<p>This study presents the design and analysis of a novel terahertz metasurface-based refractive index sensor for hemoglobin detection. The proposed sensor incorporates advanced materials including graphene, MXenes, SrTiO<sub>3</sub> and gold on a SiO<sub>2</sub> substrate. Comprehensive parametric optimization was conducted using COMSOL Multiphysics to enhance the sensor's sensitivity and overall performance. The optimized design demonstrated high sensitivity to hemoglobin concentration changes, with distinct transmittance responses observed for concentrations ranging from 10 g/l to 40 g/l. Electric field intensity analysis verified the sensor's transmission characteristics across different frequencies. Performance metrics such maximum sensitivity of 1000GHzRIU<sup>-1</sup>, minimum FOM of 2 RIU<sup>-1</sup>, minimum detection limit of 0.044 among other performance parameters which demonstrates exemplary results. Furthermore, polynomial regression models were employed to predict the sensor's behaviour under various parametric conditions, achieving maximum R<sup>2</sup> scores between 0.86 and 1 across different test cases.</p>","PeriodicalId":736,"journal":{"name":"Plasmonics","volume":"71 1","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasmonics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1007/s11468-024-02445-8","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0

Abstract

This study presents the design and analysis of a novel terahertz metasurface-based refractive index sensor for hemoglobin detection. The proposed sensor incorporates advanced materials including graphene, MXenes, SrTiO3 and gold on a SiO2 substrate. Comprehensive parametric optimization was conducted using COMSOL Multiphysics to enhance the sensor's sensitivity and overall performance. The optimized design demonstrated high sensitivity to hemoglobin concentration changes, with distinct transmittance responses observed for concentrations ranging from 10 g/l to 40 g/l. Electric field intensity analysis verified the sensor's transmission characteristics across different frequencies. Performance metrics such maximum sensitivity of 1000GHzRIU-1, minimum FOM of 2 RIU-1, minimum detection limit of 0.044 among other performance parameters which demonstrates exemplary results. Furthermore, polynomial regression models were employed to predict the sensor's behaviour under various parametric conditions, achieving maximum R2 scores between 0.86 and 1 across different test cases.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
设计和分析基于太赫兹元表面的折射率传感器,用于检测血红蛋白并利用多项式回归进行行为预测
本研究介绍了一种基于太赫兹元表面的新型折射率传感器的设计和分析,该传感器用于检测血红蛋白。拟议的传感器在二氧化硅基底上采用了石墨烯、MXenes、SrTiO3 和金等先进材料。利用 COMSOL Multiphysics 对参数进行了全面优化,以提高传感器的灵敏度和整体性能。优化后的设计对血红蛋白浓度变化具有很高的灵敏度,在 10 g/l 到 40 g/l 的浓度范围内都能观察到明显的透射响应。电场强度分析验证了传感器在不同频率下的传输特性。最大灵敏度为 1000GHzRIU-1、最小 FOM 为 2RIU-1、最小检测限为 0.044 等性能指标以及其他性能参数都显示出了良好的效果。此外,还采用了多项式回归模型来预测传感器在各种参数条件下的行为,在不同的测试案例中取得了介于 0.86 和 1 之间的最大 R2 分数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
期刊最新文献
Comparative Analysis of Two Different MIM Configurations of a Plasmonic Nanoantenna On the Transmission Line Analogy for Modeling Plasmonic Nanowire Circuits Terahertz-Multiplexed Metallic Metasurfaces for Enhanced Trace Sample Absorption Plasmonic Characteristics of LiF Filled Slab Waveguide in Isotropic Plasma Environment Synthesis, Characterization, and Modeling of Reduced Graphene Oxide Supported Adsorbent for Sorption of Pb(II) and Cr(VI) Ions from Binary Mixture
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1