Sujit Kumar Das, Smitaroopa Kahali, Dr. Sabnam Kar, Prof. Nandita Madhavan, Prof. Ankona Datta
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Abstract
We report a novel, reversible, cell-permeable, pH-sensor, TRapH. TRapH afforded a pH-sensitive ratiometric emission response in the pH range ~3–6, enabling imaging and quantification of pH in living cells. The biological-applicability of TRapH was illustrated via live-tracking of intracellular pH dynamics in living mammalian cells induced by a synthetic H+-transporter.
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