Going from Primary to Primordial Prevention: Is the Juice Worth the Squeeze?

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Cardiology Reports Pub Date : 2024-10-01 Epub Date: 2024-07-29 DOI:10.1007/s11886-024-02109-3

Andrew Chiou, Melody Hermel, Zohar Chai, Ariana Eiseman, Sheila Jeschke, Sandeep Mehta, Unab Khan, Zahra Hoodbhoy, Nilofer Safdar, Adeel Khoja, Vashma Junaid, Elizabeth Vaughan, Anwar T Merchant, Junaid Iqbal, Aysha Almas, Salim S Virani, Sana Sheikh

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Abstract

Purpose of review: While primary prevention strategies target individuals who are at high risk of cardiovascular disease, there is rising interest towards primordial prevention that focuses on preventing the development of risk factors upstream of disease detection. Therefore, we review the advantages of primordial prevention interventions on minimizing future cardiovascular events.

Recent findings: Primordial prevention of atherosclerotic cardiovascular disease involves behavioral, genetic, and environmental strategies, starting from fetal/infant health and continuing throughout childhood and young adulthood. Early interventions focusing on modifiable risk factors such as physical inactivity, non-ideal body weight, smoking, and environmental pollutants are important towards preventing the initial occurrence of risk factors such as hypertension, dyslipidemia, and diabetes to ultimately reduce cardiovascular disease. Implementing primordial prevention strategies early on in life can minimize cardiovascular events and lead to healthy aging in the population. Future studies can further evaluate the effectiveness of various primordial prevention strategies.

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从初级预防到初级预防：果汁值得一榨吗？

综述的目的：虽然一级预防策略针对的是心血管疾病的高危人群，但人们对一级预防的兴趣也在不断增加，一级预防的重点是在发现疾病之前预防危险因素的发展。因此，我们回顾了初级预防干预措施在尽量减少未来心血管事件方面的优势：动脉粥样硬化性心血管疾病的早期预防涉及行为、遗传和环境策略，从胎儿/婴儿健康开始，贯穿整个童年和青年期。早期干预侧重于可改变的风险因素，如缺乏运动、非理想体重、吸烟和环境污染，这对于预防高血压、血脂异常和糖尿病等风险因素的初期发生，最终减少心血管疾病的发生非常重要。在生命早期实施初步预防策略，可以最大限度地减少心血管事件的发生，并促进人口的健康老龄化。未来的研究可以进一步评估各种原始预防策略的有效性。

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来源期刊

Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.20

自引率

2.70%

发文量

209

期刊介绍： The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.