Evaluation of Optical Coherence Tomography Angiography in Degenerative and Tractional Lamellar Macular Hole.

IF 1.8 4区 医学 Q3 OPHTHALMOLOGY Journal of Ophthalmology Pub Date : 2024-07-19 eCollection Date: 2024-01-01 DOI:10.1155/2024/4146294
Burcu Polat Gültekin, Defne Kalaycı
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Abstract

Background: This study aims to evaluate the optical coherence tomography angiography (OCTA) findings in cases with degenerative and tractional lamellar macular holes (LMH).

Methods: Two subtypes of LMH cases were included. Seventeen patients had the degenerative subtype, whereas 18 patients had the tractional subtype of LMH. Twenty healthy individuals were enrolled as the control group. The foveal avascular zone (FAZ) and retinal vascular densities in the superficial, deep capillary, and choriocapillary plexuses were analyzed and compared with fellow eyes and healthy controls using OCTA.

Results: The mean FAZ area was wider in the degenerative subtype (0.33 ± 0.14 mm2) compared to the tractional subtype (0.24 ± 0.10 mm2) (p=0.04) and control eyes (0.26 ± 0.10 mm2) (p=0.03). Foveal vessel densities in the superficial and deep capillary plexuses were lower in the degenerative group than in the tractional group, (21.7 ± 9.8% vs. 26.8 ± 6.9%, p=0.01 and 28.5 ± 5.1% vs. 36.9 ± 6.2%, p=0.01). Choriocapillary vascular density in the parafoveal area was also lower in degenerative lamellar macular holes compared to the tractional group (60.4 ± 4.7% vs. 63.7 ± 3.9%, p=0.03). Compared to control eyes, eyes with degenerative and tractional LMH showed lower vessel densities in the parafoveal and perifoveal areas of the SCP, DCP, and all layers of CC (p < 0.05). In the foveal area, the LMH groups showed higher foveal vascular density (FVD) in the SCP than control eyes, while in the DCP, FVD was lower in the degenerative LMH eyes relative to the other groups.

Conclusion: The finding of microvascular changes between degenerative and tractional LMH subtypes highlights their distinct pathologies and supports recent changes in the classification and terminology of this macular condition.

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评估光学相干断层扫描血管造影术在退化性和牵张性片状黄斑孔中的应用。
背景:本研究旨在评估退行性和牵引性黄斑板层孔(LMH)病例的光学相干断层血管成像(OCTA)结果:本研究旨在评估退行性和牵引性黄斑板层孔(LMH)病例的光学相干断层血管造影(OCTA)结果:方法:纳入两种亚型LMH病例。方法:纳入两种亚型的 LMH 病例,其中 17 例患者为退行性亚型,18 例患者为牵引性亚型。20名健康人作为对照组。使用 OCTA 分析了眼窝无血管区(FAZ)以及浅层、深层毛细血管丛和绒毛膜毛细血管丛中的视网膜血管密度,并与同侧眼和健康对照组进行了比较:结果:与牵引亚型(0.24 ± 0.10 mm2)(P=0.04)和对照眼(0.26 ± 0.10 mm2)(P=0.03)相比,变性亚型的平均FAZ面积更大(0.33 ± 0.14 mm2)。变性组眼窝浅层和深层毛细血管丛的血管密度低于牵引组(21.7 ± 9.8% vs. 26.8 ± 6.9%,p=0.01;28.5 ± 5.1% vs. 36.9 ± 6.2%,p=0.01)。与牵引组相比,退行性片状黄斑孔旁区域的毛细血管密度也较低(60.4 ± 4.7% vs. 63.7 ± 3.9%,P=0.03)。与对照组相比,退行性和牵引性 LMH 患者的视网膜旁和视网膜周围的 SCP、DCP 以及 CC 各层的血管密度较低(P < 0.05)。在眼窝区,LMH 组的 SCP 眼窝血管密度(FVD)高于对照组,而在 DCP,退行性 LMH 眼窝血管密度低于其他组:结论:退行性LMH亚型和牵引性LMH亚型之间微血管变化的发现凸显了它们不同的病理特征,并支持了最近对这种黄斑疾病的分类和术语的改变。
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来源期刊
Journal of Ophthalmology
Journal of Ophthalmology MEDICINE, RESEARCH & EXPERIMENTAL-OPHTHALMOLOGY
CiteScore
4.30
自引率
5.30%
发文量
194
审稿时长
6-12 weeks
期刊介绍: Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.
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