Demographic and Asthma-Related Characteristics of Asthmatics Using Pressurized Metered Dose Inhalers and Dry Powder Inhalers.

IF 2 4区 医学 Q3 RESPIRATORY SYSTEM Journal of Aerosol Medicine and Pulmonary Drug Delivery Pub Date : 2024-12-01 Epub Date: 2024-07-30 DOI:10.1089/jamp.2024.0006
Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Levent Cem Mutlu, Pınar Mutlu, Görkem Vayısoğlu Şahin, Ezgi Erdem Türe, Burcu Yormaz, Aylin Çapraz, Ayşe Coşkun Beyan, Yavuzalp Solak, Funda Aksu
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Abstract

Background: Asthma controller medications can be delivered via pressurized metered dose inhaler (pMDI) or dry powder inhaler (DPI) devices. Objective: This study aimed to evaluate the frequency of exacerbations and satisfaction rate with device use in asthmatics using pMDIs or DPIs. Methods: A multicenter, cross-sectional study was conducted in adults who used pMDIs or DPIs with correct inhaler technique and good adherence for asthma treatment. Demographic and asthma-related characteristics of the subjects and data regarding device satisfaction were collected through a face-to-face interview in the outpatient clinic. Rates of pMDI and DPI users and the data were compared between the two groups. Results: The study included 338 patients (mean age: 48.6 ± 14.5 years, 253 [74.9%] women). Among participants, 96 (28.4%) were using pMDI and 242 (71.6%) were using DPI. The age of patients using pMDI were significantly lower compared with DPI users. No significant difference was observed in terms of device satisfaction and clinical outcomes of asthma between pMDI and DPI users with good inhaler technique and good adherence. Conclusion: More asthmatics use DPIs, however, pMDIs are used in younger asthmatic patients. No significant difference in terms of device satisfaction and clinical outcomes of asthma was observed between pMDI and DPI users.

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使用加压定量吸入器和干粉吸入器的哮喘患者的人口统计学特征和与哮喘相关的特征。
背景:哮喘控制药物可通过加压定量吸入器(pMDI)或干粉吸入器(DPI)装置提供。研究目的本研究旨在评估使用加压计量吸入器或干粉吸入器的哮喘患者病情加重的频率以及对设备使用的满意度。方法: 一项多中心横断面研究:在使用 pMDIs 或 DPIs 的成人中开展了一项多中心横断面研究,这些成人使用正确的吸入器技术和良好的依从性进行哮喘治疗。通过在门诊进行面对面访谈,收集了受试者的人口统计学特征、哮喘相关特征以及对设备的满意度数据。对两组 pMDI 和 DPI 使用者的比率和数据进行了比较。研究结果该研究包括 338 名患者(平均年龄:48.6 ± 14.5 岁,253 名女性[74.9%])。其中,96 人(28.4%)使用 pMDI,242 人(71.6%)使用 DPI。与使用干粉吸入器的患者相比,使用 pMDI 的患者年龄明显较低。在设备满意度和哮喘临床结果方面,使用 pMDI 和使用干粉吸入器的患者没有明显差异。结论更多的哮喘患者使用干粉吸入器,但 pMDIs 主要用于年轻的哮喘患者。在设备满意度和哮喘的临床治疗效果方面,pMDI 和 DPI 用户之间没有明显差异。
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来源期刊
CiteScore
6.70
自引率
2.90%
发文量
34
审稿时长
>12 weeks
期刊介绍: Journal of Aerosol Medicine and Pulmonary Drug Delivery is the only peer-reviewed journal delivering innovative, authoritative coverage of the health effects of inhaled aerosols and delivery of drugs through the pulmonary system. The Journal is a forum for leading experts, addressing novel topics such as aerosolized chemotherapy, aerosolized vaccines, methods to determine toxicities, and delivery of aerosolized drugs in the intubated patient. Journal of Aerosol Medicine and Pulmonary Drug Delivery coverage includes: Pulmonary drug delivery Airway reactivity and asthma treatment Inhalation of particles and gases in the respiratory tract Toxic effects of inhaled agents Aerosols as tools for studying basic physiologic phenomena.
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