Remote blood pressure management for postpartum hypertension: a cost-effectiveness analysis

IF 3.8 2区 医学 Q1 OBSTETRICS & GYNECOLOGY American Journal of Obstetrics & Gynecology Mfm Pub Date : 2024-07-27 DOI:10.1016/j.ajogmf.2024.101442
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Abstract

BACKGROUND

Recognizing the importance of close follow-up after hypertensive disorders of pregnancy, many centers have initiated programs to support postpartum remote blood pressure management.

OBJECTIVE

This study aimed to evaluate the cost-effectiveness of remote blood pressure management to determine the scalability of these programmatic interventions.

STUDY DESIGN

This was a cost-effectiveness analysis of using remote blood pressure management vs usual care to manage postpartum hypertension. The modeled remote blood pressure management included provision of a home blood pressure monitor, guidance on warning symptoms, instructions on blood pressure self-monitoring twice daily, and clinical staff to manage population-level blood pressures as appropriate. Usual care was defined as guidance on warning symptoms and recommendations for 1 outpatient visit for blood pressure monitoring within a week after discharge. This study designed a Markov model that ran over fourteen 1-day cycles to reflect the initial 2 weeks after delivery when most emergency department visits and readmissions occur and remote blood pressure management is clinically anticipated to be most impactful. Parameter values for the base-case scenario were derived from both internal data and literature review. Quality-adjusted life-years were calculated over the first year after delivery and reflected the short-term morbidities associated with hypertensive disorders of pregnancy that, for most birthing people, resolve by 2 weeks after delivery. Sensitivity analyses were performed to assess the strength and validity of the model. The primary outcome was the incremental cost-effectiveness ratio, which was defined as the cost needed to gain 1 quality-adjusted life-year. The secondary outcome was incremental cost per readmission averted. Analyses were performed from a societal perspective.

RESULTS

In the base-case scenario, remote blood pressure management was the dominant strategy (ie, cost less, higher quality-adjusted life-years). In univariate sensitivity analyses, the most cost-effective strategy shifted to usual care when the cost of readmission fell below $2987.92 and the rate of reported severe range blood pressure with a response in remote blood pressure management was <1%. Assuming a willingness to pay of $100,000 per quality-adjusted life-year, using remote blood pressure management was cost-effective in 99.28% of simulations in a Monte Carlo analysis. Using readmissions averted as a secondary effectiveness outcome, the incremental cost per readmission averted was $145.00.

CONCLUSION

Remote blood pressure management for postpartum hypertension is cost saving and has better outcomes than usual care. Our data can be used to inform future dissemination of and support funding for remote blood pressure management programs.

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产后高血压的远程血压管理:成本效益分析。
背景:认识到妊娠期高血压疾病(HDP)后密切随访的重要性,许多医疗中心都启动了产后远程血压管理(RBPM)项目:认识到妊娠期高血压疾病(HDP)后密切随访的重要性,许多中心已启动了支持产后远程血压管理(RBPM)的项目:研究设计:我们对利用 RBPM 管理产后高血压与常规护理进行了成本效益分析。示范 RBPM 包括提供家用血压计、关于预警症状的指导、每天两次的血压自我监测指导以及根据情况管理人群血压的临床人员。常规护理的定义是提供有关预警症状的指导,并建议患者在出院后一周内到门诊进行一次血压监测。我们设计了一个马尔可夫模型,该模型运行了 14 个为期一天的周期,以反映产后最初两周的情况,这两周是大多数急诊室就诊和再入院发生的时间,临床上预计 RBPM 的影响最大。基础方案的参数值来自内部数据和文献综述。产后第一年的 QALY 计算反映了与 HDP 相关的短期发病率,对于大多数分娩者来说,这些发病率在产后两周内就会消除。为评估模型的强度和有效性,进行了敏感性分析。主要结果是增量成本效益比 (ICER),定义为获得一个质量调整生命年 (QALY) 所需的成本。次要结果是每次避免再入院的增量成本。从社会角度进行了分析:在基础方案中,使用 RBPM 是最主要的策略(即成本更低、质量调整生命年更高)。在单变量敏感性分析中,当再入院费用低于 2,987.92 美元,且 RBPM 有反应的重度血压范围报告率低于 1%时,最具成本效益的策略将转向常规护理。假设每 QALY 的支付意愿为 100,000 美元,在蒙特卡罗分析中,99.28% 的模拟结果显示使用 RBPM 具有成本效益。将避免再入院作为次要有效性结果,每次避免再入院的增量成本为 145.00 美元:与常规护理相比,产后高血压的远程血压管理可节约成本并获得更好的疗效。这些数据可用于今后远程血压管理项目的推广和资金支持。
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来源期刊
CiteScore
7.40
自引率
3.20%
发文量
254
审稿时长
40 days
期刊介绍: The American Journal of Obstetrics and Gynecology (AJOG) is a highly esteemed publication with two companion titles. One of these is the American Journal of Obstetrics and Gynecology Maternal-Fetal Medicine (AJOG MFM), which is dedicated to the latest research in the field of maternal-fetal medicine, specifically concerning high-risk pregnancies. The journal encompasses a wide range of topics, including: Maternal Complications: It addresses significant studies that have the potential to change clinical practice regarding complications faced by pregnant women. Fetal Complications: The journal covers prenatal diagnosis, ultrasound, and genetic issues related to the fetus, providing insights into the management and care of fetal health. Prenatal Care: It discusses the best practices in prenatal care to ensure the health and well-being of both the mother and the unborn child. Intrapartum Care: It provides guidance on the care provided during the childbirth process, which is critical for the safety of both mother and baby. Postpartum Issues: The journal also tackles issues that arise after childbirth, focusing on the postpartum period and its implications for maternal health. AJOG MFM serves as a reliable forum for peer-reviewed research, with a preference for randomized trials and meta-analyses. The goal is to equip researchers and clinicians with the most current information and evidence-based strategies to effectively manage high-risk pregnancies and to provide the best possible care for mothers and their unborn children.
期刊最新文献
Activity restriction and risk of adverse pregnancy outcomes Oxytocin regimen used for induction of labor and pregnancy outcomes. Results of the RE-DINO multicenter randomized trial on the repeated use of vaginal dinoprostone (Propess®) for labor induction in patients at term. Corrigendum to ‘Prevention of preterm birth in twin pregnancies’ American Journal of Obstetrics & Gynecology MFM/ Volume 4 (2022) 100551 Validation of the PROMIS© Medication Adherence Scale for Pregnant Patients Taking Aspirin.
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