A review of research status of self-healing hydrogels for treating a diabetic wound

Abstract

Diabetes presents a challenge in wound healing management due to its propensity to lead to chronic non-healing wounds and injuries. Due to neurotherapy and dysfunction of the immune system, impaired wound sensation is caused. Over time, such factors hinder wound detection and create a condition prone to infection and inflammation. Consequently, these wounds demand specialized interventions for successful resolution. Self-healing hydrogels appear as a solution, possessing the remarkable ability to autonomously repair damage sustained during use, mimicking the regenerative ability of native tissues. These advanced materials offer extensive benefits in wound management. Their rapid restoration of the structure upon mechanical disruption ensures prolonged contact with wound sites, maintaining an optimal healing environment. This review explores the current advances made in self-healing hydrogels as an effective and efficient biomaterial through their properties for addressing these challenges in diabetic wound treatment. With wound dressings playing an important role in promoting healing and preventing infections, this review focuses on self-healing hydrogels potential to revolutionize wound care practices.