Trifecta of Tumors: Simultaneous Detection of Three Primary Malignancies by Different Radiotracers of Nuclear Medicine

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING World Journal of Nuclear Medicine Pub Date : 2024-07-24 DOI:10.1055/s-0044-1788738
Siven Kar, Harshita Gupta, Nusrat Shaikh, V. Lele
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Abstract

Malignancies are increasing worldwide with changing lifestyle, pollution, increasing life expectancy, and diagnostic advancements. However, multiple primary malignancies (MPMs) detected simultaneously are very rare. Here, we present a rare case of three primary malignancies (sigmoid colon, prostate, and thyroid) detected simultaneously in a 77-year-old male patient, who initially presented with bleeding per rectum and was then found to have a large pedunculated mass in the sigmoid colon on colonoscopy, which further turned out to be adenocarcinoma. On further imaging and investigations, two new separate malignancies (prostate and thyroid) were found by two different positron emission tomography radiotracers: prostate-specific membrane antigen (PSMA) and fluorodeoxyglucose (FDG). Hence, nuclear medicine modalities can play an important role in detecting MPMs using the vast array of radiotracers available now and perhaps reduce the need for multiple biopsies.
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肿瘤三部曲用核医学的不同放射性同位素同时检测三种原发性恶性肿瘤
随着生活方式的改变、污染、预期寿命的延长以及诊断技术的进步,恶性肿瘤在全球范围内呈上升趋势。然而,同时发现多种原发性恶性肿瘤(MPMs)的情况非常罕见。这里,我们介绍一例罕见的同时发现三种原发性恶性肿瘤(乙状结肠、前列腺和甲状腺)的病例,患者 77 岁,最初因直肠出血就诊,结肠镜检查发现乙状结肠有一个巨大的梗阻性肿块,进一步检查发现是腺癌。在进一步的成像和检查中,通过两种不同的正电子发射断层扫描放射性核素:前列腺特异性膜抗原(PSMA)和氟脱氧葡萄糖(FDG),发现了两个新的独立恶性肿瘤(前列腺和甲状腺)。因此,核医学模式可在利用现有的大量放射性示踪剂检测 MPM 方面发挥重要作用,或许还能减少多次活检的需要。
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来源期刊
World Journal of Nuclear Medicine
World Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
16.70%
发文量
118
审稿时长
48 weeks
期刊最新文献
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