The use of high dose inhaled beclomethasone dipropionate as a means of assessing steroid responsiveness in obstructive airways disease

A.G. Wardman, F.G. Simpson, A.J. Knox, R.L. Page, N.J. Cooke
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引用次数: 18

Abstract

The use of high dose inhaled beclomethasone dipropionate (BDP) as a means of assessing steroid responsiveness in chronic obstructive airways disease (COAD) was assessed in 22 patients in a study involving three consecutive 2-week periods of placebo, inhaled BDP (1500 μg daily), and oral prednisolone (30 mg daily). Five of the 22 patients were considered steroid responsive following the course of oral corticosteroids and in each case this responsiveness had been identified by inhlaed BDP therapy. It is concluded that high dose inhaled BDP (1500 μg daily) may be used to assess corticosteroid responsiveness in COAD.

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使用大剂量吸入二丙酸倍氯米松作为评估阻塞性气道疾病中类固醇反应性的手段
使用高剂量吸入二丙酸倍氯米松(BDP)作为评估慢性阻塞性气道疾病(COAD)类固醇反应性的手段,在一项研究中对22例患者进行了评估,该研究包括连续3个2周的安慰剂、吸入BDP(每天1500 μg)和口服强的松龙(每天30 mg)。22例患者中有5例在口服皮质类固醇治疗后被认为是类固醇反应性的,在每个病例中,这种反应性都是通过植入BDP治疗来确定的。因此,高剂量吸入BDP(每日1500 μg)可用于评估COAD患者的皮质类固醇反应性。
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