HPV vaccines and a future without cervical cancer in sub-Saharan Africa

Michael Ezeanochie
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Abstract

Cervical cancer remains a global public health problem with the annual number of new cases and deaths projected to increase to 700000 and 400,000 in 2030, respectively. Unfortunately, about 85% of woman affected by cervical cancer are young, undereducated and live in the world’s poorest regions like sub-Saharan Africa including Nigeria. Although high income countries (HIC) have reduced morbidity and mortality from cervical cancer by about 80% using cytology (pap smears) for population-based screening cervices in the past 60 years, many low-middle-income-countries (LMIC) in sub-Saharan Africa have not been able to replicate it due to limited resources and challenges with the personnel, laboratory and logistics requirements, competing health needs and the appropriate political commitment. Addressing the barriers to achieving the 90:70:90 targets by 2030 will help the region towards a sustainable pathway to eliminate cervical cancer by 2120.
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HPV 疫苗和撒哈拉以南非洲没有宫颈癌的未来
宫颈癌仍然是一个全球性的公共卫生问题,预计到 2030 年,每年新增病例和死亡人数将分别增至 70 万和 40 万。不幸的是,约 85% 的宫颈癌患者是年轻女性,她们受教育程度低,生活在世界上最贫穷的地区,如撒哈拉以南非洲,包括尼日利亚。尽管高收入国家(HIC)在过去的 60 年里利用细胞学检查(子宫颈抹片检查)开展了以人口为基础的筛查服务,将宫颈癌的发病率和死亡率降低了约 80%,但撒哈拉以南非洲的许多中低收入国家(LMIC)却因资源有限、人员、实验室和物流要求方面的挑战、相互竞争的健康需求以及适当的政治承诺而无法效仿。消除到 2030 年实现 90:70:90 目标的障碍,将有助于该地区走上到 2120 年消除宫颈癌的可持续发展道路。
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