{"title":"Agenesis of Corpus Callosum in a Fetus at 22 Weeks: Role of MRI Based Scoring and MR Tractography in Clinical Decision Making","authors":"N. Ghonge","doi":"10.1055/s-0044-1788300","DOIUrl":null,"url":null,"abstract":"A 32 year old woman at 22 weeks gestation underwent fetal magnetic resonance imaging (MRI) after an ultrasound detected corpus callosum agenesis. MRI confirmed complete agenesis and showed an enlarged left temporal lobe, moderate ventriculomegaly, and abnormal hippocampal orientation. The fetal MRI scoring system indicated a poor prognosis. MR tractography revealed abnormal neuronal connections. Parents were counseled and the pregnancy was terminated due to poor prognosis. This case highlights the value of fetal MRI and tractography in assessing agenesis of the corpus callosum and guiding clinical decisions.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":null,"pages":null},"PeriodicalIF":0.1000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fetal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0044-1788300","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
A 32 year old woman at 22 weeks gestation underwent fetal magnetic resonance imaging (MRI) after an ultrasound detected corpus callosum agenesis. MRI confirmed complete agenesis and showed an enlarged left temporal lobe, moderate ventriculomegaly, and abnormal hippocampal orientation. The fetal MRI scoring system indicated a poor prognosis. MR tractography revealed abnormal neuronal connections. Parents were counseled and the pregnancy was terminated due to poor prognosis. This case highlights the value of fetal MRI and tractography in assessing agenesis of the corpus callosum and guiding clinical decisions.
期刊介绍:
Journal of Fetal Medicine is the official journal of the Society of Fetal Medicine affiliated with International Society of Ultrasound in Obstetrics & Gynecology. This is a peer-reviewed international journal featuring articles with special interest to fetal medicine specialists, geneticists and ulstrasonologists. The aim of the journal is to communicate the results of original research in the field of fetal medicine. It includes a variety of articles suitable for clinicians and scientific specialists concerned with diagnosis and therapy of fetal disorders. All articles on health promotion of the fetus are acceptable for publication. The major focus is on highlighting the work that has been carried out in India and other developing countries. It also includes articles written by experts from the West. Types of articles published: - Original research articles related to fetal care and basic research - Review articles - Consensus guidelines for diagnosis and treatment - Case reports - Images in Fetal Medicine - Brief communications