ANALYSIS OF ANTIBIOTIC CONSUMPTION IN THE NATIONAL CENTER OF CHILDREN’S REHABILITATION FOR 2019- 2020 IN THE CONDITIONS OF THE COVID-19 PANDEMIC

L.G. Makalkina, M.Zh. Shakenov, A.N. Ihambaeva, Zh.A. Seikenova, U.Sh. Abdrakhmanova, K.K. Kusainova, N.T. Aldiyarova
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Abstract

The COVID-19 pandemic has posed a major challenge for all humanity and health systems in all countries. Excessive and unjustified use of antibiotics is one of the most important factors in the development of antibiotic resistance. Objective of the study: to identify the dynamics of antibiotic consumption in a children’s rehabilitation center during the COVID-19 pandemic for 2019-2020 and to identify factors affecting the incidence of infectious diseases and the consumption of antibiotics. Research methods: the calculation of antibiotic consumption was carried out according to the ATC / DDD methodology of the WHO Collaborating Center for Drug Statistics Methodology using the WHO database [4] to assign the ATC index and DDD values of drugs Results: The total consumption of antibacterial agents for systemic use (group J01) showed a decrease in DBD in 2020 compared to 2019 by 40% and amounted to 39.29 DBD in 2019 and 28.04 DBD in 2020. When assessing dynamic consumption antibiotics on arrival, we have identified a downward trend in antibiotic consumption after the introduction of strict quarantine measures at the Center. That, combined with data for 2020 on a decrease in the number of patients who were prescribed antibiotics and a decrease in the number of antibiotics per patient, showed the high effectiveness of restrictive measures at the Center related to the COVID-19 pandemic. Conclusions: the results of the study of antibiotic consumption for 2019-2020. according to the ATC / DDD methodology, it revealed an overall decrease in consumption in 2020 compared to 2019 by 40%, which is a positive result of the strict quarantine measures and an increase in the justification for prescribing antibiotics at the Center during the COVID-19 pandemic.
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2019-2020 年国家儿童康复中心在科维德-19 大流行病条件下的抗生素消耗分析
COVID-19 大流行给全人类和所有国家的卫生系统带来了重大挑战。过度和不合理使用抗生素是导致抗生素耐药性产生的最重要因素之一。研究目的:确定2019-2020年COVID-19大流行期间儿童康复中心的抗生素消耗动态,并找出影响传染病发病率和抗生素消耗的因素。研究方法:根据世界卫生组织药品统计方法合作中心的 ATC / DDD 方法,利用世界卫生组织数据库[4]分配药品的 ATC 指数和 DDD 值,进行抗生素消耗量的计算 结果:2020年全身用抗菌药(J01组)的DBD总消费量与2019年相比下降了40%,2019年为39.29DBD,2020年为28.04DBD。在评估运抵时抗生素的动态消耗量时,我们发现在中心采取严格的检疫措施后,抗生素消耗量呈下降趋势。这与 2020 年开具抗生素处方的患者人数减少和每位患者使用抗生素数量减少的数据相结合,表明该中心与 COVID-19 大流行相关的限制性措施非常有效。结论:根据 ATC / DDD 方法,对 2019-2020 年抗生素消耗量的研究结果显示,2020 年的抗生素消耗量比 2019 年总体减少了 40%,这是严格检疫措施的积极成果,也增加了 COVID-19 大流行期间中心开具抗生素处方的合理性。
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