Laser technologies in the treatment of patients with a combination of rosacea subtypes: comparative data

A. L. Rodina, Yu. I. Matushevskaya, G. V. Sofinskaya
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Abstract

Phototechnologies occupy a leading position in the treatment of patients with rosacea. The most effective technologies are laser: pulsed dye laser (585nm, 595nm) and neodymium laser (1064nm), however, issues of comparative analysis, including in patients with a combination of rosacea subtypes, require further study.Material and methods. We observed 64 patients with diagnosed rosacea with a combination of subtypes: erythematotelangiectatic and papulopustular. Among them, 48 (75%) were female and 16 (25%) were male. The age of the patients varied widely: from 31 to 57 years, the average age was 39.2±4.6 years. The average duration of the disease was 5.1±2.3 years. Depending on the therapy, patients were divided into 2 groups: group 1 received treatment with a neodymium laser, group 2 – treatment with a pulsed dye laser.Research results. A cumulative assessment taking into account clinical research methods with a sufficient degree of reliability revealed the advantages of a neodymium laser over a pulsed dye laser, regardless of the clinical picture of rosacea, which was confirmed by the dynamics of the IGA/PGA indices: reduction in group 1 was 79.5%/66.7%, in group 2–63.2%/51.3%, respectively. These data were confirmed by the dynamics of the DIQI index – 81.7% and 61.6%, respectively.
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激光技术在红斑痤疮综合亚型患者治疗中的应用:比较数据
光电技术在酒糟鼻患者的治疗中占据主导地位。最有效的技术是激光:脉冲染料激光(585nm、595nm)和钕激光(1064nm),然而,需要进一步研究比较分析的问题,包括酒糟鼻亚型组合患者的比较分析。我们观察了 64 名确诊为酒渣鼻的患者,他们都有不同的亚型:红斑扩张型和丘疹脓疱型。其中,女性 48 人(占 75%),男性 16 人(占 25%)。患者的年龄差异很大:从 31 岁到 57 岁不等,平均年龄为(39.2±4.6)岁。平均病程为 5.1±2.3 年。根据治疗方法的不同,患者被分为两组:第一组接受钕激光治疗,第二组接受脉冲染料激光治疗。根据具有足够可靠性的临床研究方法进行的累积评估显示,无论红斑痤疮的临床表现如何,钕激光都比脉冲染料激光更有优势,这一点在 IGA/PGA 指数的动态变化中得到了证实:第一组的减少率分别为 79.5%/66.7%,第二组为 63.2%/51.3%。DIQI 指数的动态变化也证实了这些数据--分别为 81.7% 和 61.6%。
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