Takotsubo Syndrome Associated with Neurally Mediated Reflex Syncope: A Meta-summary of Case Reports and Literature Review

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-07-15 DOI:10.31083/j.rcm2507264
Vincenzo Russo, Filippo Pecori, Nicola Colalillo, Nicola Massimo, Giovanni Battista Valentino, A. Comune, E. Parente, G. Nigro
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Abstract

Background : Neurally mediated reflex syncope (NMRS) has been recently described as a possible trigger of Takotsubo syndrome (TTS). There are few data in the literature about this association. Methods : In the present meta-summary, 6 case reports describing patients who experienced TTS following an NMRS episode were included. Patient characteristics, triggers and type of syncope were collected. Results : A total of 7 patients with a median age of 63.4 years (interquartile range, IQR: 47.5–76) were evaluated; 71.4% were females, mainly in the menopausal state (80%). The TTS triggers were: vasovagal syncope in 6 patients (85.7%) and situational syncope in 1 patient (14.3%). 2 patients underwent a comprehensive clinical evaluation which showed a cardioinhibitory response. Conclusions : NMRS due to sudden orthostatism and emotional stress, mainly with a cardioinhibitory response, has been associated with the onset of TTS, in particular among female patients in a
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与神经介导的反射性晕厥相关的塔克次氏综合征:病例报告和文献综述的元总结
背景:神经介导的反射性晕厥(NMRS)最近被描述为可能诱发塔克次氏综合征(TTS)的一个因素。有关这种关联的文献资料很少。方法:在本综述中,纳入了 6 份病例报告,这些报告描述了在 NMRS 发作后出现 TTS 的患者。收集了患者特征、诱因和晕厥类型。结果:共评估了 7 名患者,中位年龄为 63.4 岁(四分位间距:47.5-76);71.4% 为女性,主要处于绝经状态(80%)。TTS 的诱因是:6 名患者(85.7%)的血管迷走性晕厥和 1 名患者(14.3%)的情景性晕厥。2 名患者接受了全面的临床评估,评估结果显示存在心脏抑制反应。结论 :由突发性正位和情绪紧张引起的 NMRS(主要伴有心脏抑制反应)与 TTS 的发病有关,尤其是在女性患者中。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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