{"title":"Tibial fracture arising from bone amyloidosis: A case study","authors":"Akane Yamamoto , Tomoaki Fukui , Takahiro Niikura , Kenichi Sawauchi , Masato Komatsu , Ryosuke Kuroda , Keisuke Oe","doi":"10.1016/j.joscr.2024.07.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Amyloidosis, a disease characterized by the deposition of abnormal proteins in various organs, leads to functional disorders. Here, we report the case of a 63-year-old man with AL amyloid deposition in the tibial shaft that resulted in a tibial fracture.</div></div><div><h3>Case presentation</h3><div>Amyloid bone cysts typically occur in the joints and vertebrae of patients undergoing hemodialysis; however, in this case, the patient was not undergoing dialysis, and the deposition site was the tibial shaft. We performed curettage and osteosynthesis using a plate, and satisfactory patient recovery was observed at a 1.5-year postoperative follow-up.</div></div><div><h3>Conclusions</h3><div>Amyloidosis may cause functional impairment due to amyloid deposits in multiple organs and other complications; therefore, systemic examination is necessary.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 1","pages":"Pages 19-23"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JOS Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772964824000303","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/25 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Background
Amyloidosis, a disease characterized by the deposition of abnormal proteins in various organs, leads to functional disorders. Here, we report the case of a 63-year-old man with AL amyloid deposition in the tibial shaft that resulted in a tibial fracture.
Case presentation
Amyloid bone cysts typically occur in the joints and vertebrae of patients undergoing hemodialysis; however, in this case, the patient was not undergoing dialysis, and the deposition site was the tibial shaft. We performed curettage and osteosynthesis using a plate, and satisfactory patient recovery was observed at a 1.5-year postoperative follow-up.
Conclusions
Amyloidosis may cause functional impairment due to amyloid deposits in multiple organs and other complications; therefore, systemic examination is necessary.