Evidence-based use of epinephrine in anaphylaxis.

IF 3 4区 医学 Q2 ALLERGY Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-29 DOI:10.1097/ACI.0000000000001009
Catherine Hammond, Jay Adam Lieberman
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Abstract

Purpose of review: Epinephrine is the first line treatment for anaphylaxis, however, there are limited data to support this. This review examines data surrounding evidence for the use of epinephrine in anaphylaxis, data on prescription for and use of epinephrine autoinjectors, and data examining newer routes of delivery of epinephrine; with a focus on recent publications over the past few years.

Recent findings: With recent epidemiologic studies of anaphylaxis and new forms of epinephrine being studied, new data on the effects of epinephrine are aiding in the understanding of epinephrine's effects and the shortcomings of epinephrine both in its effect and utility in the real world.

Summary: Epinephrine is still considered the first line therapy for anaphylaxis, and we are starting to have a better understanding of its effects in both healthy patients and those with anaphylaxis.

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根据证据使用肾上腺素治疗过敏性休克。
审查目的:肾上腺素是治疗过敏性休克的一线药物,但支持这一观点的数据有限。本综述研究了过敏性休克使用肾上腺素的相关证据数据、肾上腺素自动注射器的处方和使用数据以及肾上腺素新给药途径的研究数据;重点关注过去几年的最新出版物:摘要:肾上腺素仍被认为是治疗过敏性休克的一线疗法,我们开始更好地了解肾上腺素对健康患者和过敏性休克患者的作用。
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来源期刊
CiteScore
5.90
自引率
3.60%
发文量
109
审稿时长
6-12 weeks
期刊介绍: This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on one to three topics, every issue of Current Opinion in Allergy and Clinical Immunology delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as upper airway disease; mechanisms of allergy and adult asthma; paediatric asthma and development of atopy; food and drug allergies; and immunotherapy.
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