Post-mortem diagnosis of human rabies in SARS-CoV-2 coinfected patient with minimally invasive autopsy in northeastern Brazil.

IF 1.4 4区 医学 Q4 INFECTIOUS DISEASES Journal of Infection in Developing Countries Pub Date : 2024-07-29 DOI:10.3855/jidc.19427
Luis Arthur Bg Farias, Marcos M Sousa, Ruth Maria O De Araujo, Kelma M Maia, Madalena Q De Azevedo, Nancy C De Oliveira Caetano, Karene F Cavalcante, Liana P Mello, Larissa Leao F De Sousa, Sami de Andrade C Gadelha, Deborah N De Melo, Ana Karine B Carneiro, Tânia Mara S Coelho, Antônio Silva L Neto, Francisco Edson B Abreu, Kellyn Kessiene de S Cavalcante, Silvia F Costa, Luciano P De Goes Cavalcanti, Lauro V Perdigão Neto
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Abstract

Introduction: Human rabies (HR) is a lethal zoonotic disease caused by lyssaviruses with increase in the number of cases post-coronavirus disease 2019 (COVID-19) pandemic.

Methodology: We report a case of human rabies in a patient from a rural area of Ceará, northeastern Brazil in 2023, who was bitten by a white-tufted-ear marmoset (Callithrix jacchus jacchus). The patient was co-infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and was diagnosed by minimally invasive autopsy (MIA).

Results: MIA offers many advantages related to biosafety, and speed of sample acquisition; and markedly reduces disfigurement of the body compared with complete autopsy. It is a great alternative in COVID-19 patients.

Conclusions: New methods such as MIA are a promising tool for diagnosis, and have the potential to improve family cooperation and support rabies surveillance.

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在巴西东北部通过微创尸检对 SARS-CoV-2 共感染患者进行死后人类狂犬病诊断。
简介:人类狂犬病(HR)是一种由舔病毒引起的致命性人畜共患病:人类狂犬病(HR)是一种由深裂病毒引起的致命性人畜共患病,在2019年冠状病毒病(COVID-19)大流行后病例数量有所增加:我们报告了 2023 年巴西东北部塞阿拉农村地区的一例人类狂犬病病例,该患者被一只白尾耳狨(Callithrix jacchus jacchus)咬伤。该患者同时感染了严重急性呼吸系统综合征冠状病毒-2(SARS-CoV-2),并通过微创尸检(MIA)确诊:结果:微创尸检在生物安全和样本采集速度方面具有很多优势,与完全尸检相比,微创尸检明显减少了对身体的毁损。对于 COVID-19 患者来说,这是一种很好的替代方法:结论:MIA 等新方法是一种很有前途的诊断工具,有可能改善家庭合作并支持狂犬病监测。
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来源期刊
CiteScore
3.70
自引率
5.30%
发文量
239
审稿时长
4-8 weeks
期刊介绍: The Journal of Infection in Developing Countries (JIDC) is an international journal, intended for the publication of scientific articles from Developing Countries by scientists from Developing Countries. JIDC is an independent, on-line publication with an international editorial board. JIDC is open access with no cost to view or download articles and reasonable cost for publication of research artcles, making JIDC easily availiable to scientists from resource restricted regions.
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