Cardiac Arrest Due to Capecitabine Toxicosis Treated With ECMO and CRRT: A Case Report.

IF 2 4区 医学 Q3 CRITICAL CARE MEDICINE Critical care nurse Pub Date : 2024-08-01 DOI:10.4037/ccn2024858
Liqin Zhang, Mingjun Liu, Lutao Xie, Xin Tian
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引用次数: 0

Abstract

Introduction: This is the first report of a patient who developed cardiogenic shock after receiving oral chemotherapy with capecitabine and was treated with venoarterial extracorporeal membrane oxygenation combined with continuous renal replacement therapy.

Clinical findings: A 58-year-old man developed an arrhythmia that rapidly progressed to cardiogenic shock and cardiac arrest after receiving oral capecitabine tablets to treat a rectal malignancy.

Interventions: The patient was treated with venoarterial extracorporeal membrane oxygenation in combination with continuous renal replacement therapy.

Outcome: The patient made a full recovery and was discharged from the hospital.

Conclusion: The use of comprehensive supportive treatments such as extracorporeal membrane oxygenation combined with continuous renal replacement therapy in patients with capecitabine-induced cardiac arrest can rapidly reduce drug concentrations, eliminate harmful substances, and improve the prognosis.

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用 ECMO 和 CRRT 治疗卡培他滨中毒导致的心脏骤停:病例报告。
导言:这是首次报道一名患者在接受卡培他滨口服化疗后出现心源性休克,并接受静脉体外膜肺氧合联合持续肾脏替代治疗:一名58岁的男性在口服卡培他滨片治疗直肠恶性肿瘤后出现心律失常,并迅速发展为心源性休克和心脏骤停:干预措施:患者接受了静脉体外膜肺氧合治疗和持续肾脏替代治疗:结果:患者完全康复出院:结论:对卡培他滨诱发的心脏骤停患者采用体外膜肺氧合联合持续肾脏替代治疗等综合支持治疗,可迅速降低药物浓度,清除有害物质,改善预后。
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来源期刊
Critical care nurse
Critical care nurse 医学-护理
CiteScore
2.80
自引率
0.00%
发文量
68
审稿时长
>12 weeks
期刊介绍: Critical Care Nurse (CCN) is an official publication of the American Association of Critical-Care Nurses (AACN). Authors are invited to submit manuscripts for consideration and peer review. Clinical topics must meet the mission of CCN and address nursing practice of acute and critically ill patients.
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