[Treatment of T1 colorectal cancer].

Q4 Medicine Nederlands tijdschrift voor geneeskunde Pub Date : 2024-07-24
Nina C A Vermeer, Leon M G Moons, Jurjen J Boonstra, Fabian A Holman, Miangela M Laclé, Koen C M J Peeters
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引用次数: 0

Abstract

In case of suspicion of a T1 colorectal tumor, the tumor should not be biopsied but removed completely (so-called en-bloc resection). With more recent endoscopic techniques, T1 colorectal tumors can be more often radical resected. If at least one of the following four characteristics is present, there is a high-risk T1 colorectal tumor and it is recommended to consider surgical resection with adequate lymphadenectomy; poor differentiation, presence of (lymphatic) angioinvasion, high-grade tumor budding (grade 2-3) and a positive resection margin (where the malignant cells approach the cut edge to 0.1mm). The risk of recurrent disease after endoscopic resection of a high-risk T1 colorectal tumor without additional surgery is not well known. Scheduled surgery for bowel cancer at an early stage is associated with the same risk of a serious complication and/or death as scheduled surgery at a more advanced stage.

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[T1 结直肠癌的治疗]。
如果怀疑是 T1 结直肠肿瘤,则不应进行活检,而应将肿瘤完全切除(即所谓的全切)。随着内窥镜技术的发展,T1 结直肠肿瘤可以更多地被根治性切除。如果存在以下四个特征中的至少一个,则为高危 T1 结直肠肿瘤,建议考虑手术切除并充分切除淋巴结;分化差、存在(淋巴)血管侵犯、高级别肿瘤出芽(2-3 级)和切除边缘阳性(恶性细胞接近切缘 0.1 毫米)。内镜下切除高风险 T1 结直肠肿瘤而不进行额外手术后,复发疾病的风险尚不清楚。肠癌早期手术与晚期手术发生严重并发症和/或死亡的风险相同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Nederlands tijdschrift voor geneeskunde
Nederlands tijdschrift voor geneeskunde Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
302
期刊介绍: Het NTVG staat bekend als hét wetenschappelijke algemene medische tijdschrift. De lange historie en de degelijkheid maken het tijdschrift tot een bolwerk van medische wetenschap in druk. Ook door de goede leesbaarheid draagt het tijdschrift bij aan de voortdurende dialoog over de geneeskunde.
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