Retropharyngeal Abscess Complicated by Mediastinitis in Infants.

IF 3.5 3区 医学 Q2 RESPIRATORY SYSTEM Respiration Pub Date : 2024-01-01 Epub Date: 2024-07-31 DOI:10.1159/000540525
Ann Thomas, Shaun Adam, Pierre Goussard, Shyam Sunder B Venkatakrishna, Savvas Andronikou, Johan Grobbelaar
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Abstract

Introduction: Most paediatric upper respiratory infections are virally mediated and result in self-limiting reactive lymphadenopathy. In children younger than 5 years, retropharyngeal lymph nodes may give rise to deep neck space infections in this potential space. Retropharyngeal infections are rare after 5 years because lymph nodes undergo atrophy.

Methods: We present a series of 6 cases of paediatric retropharyngeal abscesses (RPA) complicated by mediastinitis, managed at a tertiary hospital over a 4-year period.

Results: All our cases presented with fever, difficulty feeding, and neck swelling. The age range was 11 weeks-11 months, and all tested negative for human immunodeficiency virus. The diagnosis and complications were confirmed on computed tomography (CT) scan. The CT scans consistently revealed RPA with varying degrees of deep neck space and mediastinal extension. All children were promptly taken to theatre for source control. Two were extubated successfully immediately after surgery, and the other 4 were extubated in the paediatric intensive care unit, with the longest duration of intubation being 3 days. Methicillin-sensitive Staphylococcus aureus (MSSA) was cultured in all 6 cases.

Conclusion: Management of these cases may be challenging, and young children with RPA require close care and airway monitoring. CT or magnetic resonance imaging is essential to delineate the extent of infection. Surgical drainage should be performed when there is a large abscess, a complication occurs, or an inadequate response in 24-48 h to medical management.

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婴儿咽后脓肿并发纵隔炎。
导言大多数儿科上呼吸道感染都是由病毒介导的,并导致自限性反应性淋巴结病。在 5 岁以下儿童中,咽后淋巴结可能在这一潜在空间引起颈深间隙感染。由于淋巴结会发生萎缩,因此 5 岁以后很少发生咽后感染:我们介绍了一家三甲医院在 4 年内处理的 6 例并发纵隔炎的小儿咽后脓肿(RPA)病例:所有病例均伴有发热、喂养困难和颈部肿胀。病例年龄在 11 周至 11 个月之间,所有病例的人类免疫缺陷病毒(HIV)检测结果均为阴性。计算机断层扫描(CT)证实了诊断和并发症。CT 扫描结果一致显示咽后脓肿,并有不同程度的颈深间隙和纵隔扩展。所有患儿都被立即送往手术室进行源头控制。两名患儿在术后立即成功拔管,另外四名患儿在重症监护病房拔管,其中插管时间最长的为 3 天。所有 6 例病例均培养出甲氧西林敏感金黄色葡萄球菌(MSSA):这些病例的处理可能具有挑战性,患有 RPA 的幼儿需要密切护理和气道监测。CT 或磁共振成像(MRI)对确定感染范围至关重要。如果脓肿较大、出现并发症或在 24-48 小时内药物治疗效果不佳,则应进行手术引流。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Respiration
Respiration 医学-呼吸系统
CiteScore
7.30
自引率
5.40%
发文量
82
审稿时长
4-8 weeks
期刊介绍: ''Respiration'' brings together the results of both clinical and experimental investigations on all aspects of the respiratory system in health and disease. Clinical improvements in the diagnosis and treatment of chest and lung diseases are covered, as are the latest findings in physiology, biochemistry, pathology, immunology and pharmacology. The journal includes classic features such as editorials that accompany original articles in clinical and basic science research, reviews and letters to the editor. Further sections are: Technical Notes, The Eye Catcher, What’s Your Diagnosis?, The Opinion Corner, New Drugs in Respiratory Medicine, New Insights from Clinical Practice and Guidelines. ''Respiration'' is the official journal of the Swiss Society for Pneumology (SGP) and also home to the European Association for Bronchology and Interventional Pulmonology (EABIP), which occupies a dedicated section on Interventional Pulmonology in the journal. This modern mix of different features and a stringent peer-review process by a dedicated editorial board make ''Respiration'' a complete guide to progress in thoracic medicine.
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