A. V. Bobrova, E. I. Golenko, A. V. Oberenko, T. Y. Ivanenko, E. V. Root, G. A. Suboch
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引用次数: 0
Abstract
The behavior of N-Substituted 3,5-dimethyl-4-nitroso-1H-pyrazoles in oxidation, condensation, and reduction reactions was studied. The synthesized 4-aminopyrazole was acylated and diazotized with further azo coupling or the replacement of the amino group by iodine, as well as subjected to condensation with 4-nitrobenzaldehyde. The first condensation of nitrosopyrazole with 2,4-dinitrotoluene was demonstrated. As a result, new functionalized pyrazole derivatives were isolated. The structure of the novel pyrazoles was confirmed by IR and 1H and 13C NMR spectroscopy, gas chromatography-mass spectrometry, and elemental analysis. The synthesized compounds hold promise for further research in medicine and pharmaceutical chemistry.
期刊介绍：
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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